|
The conjugated linoleic acid (CLA) isomer, t10c12-CLA, is inversely associated with changes in body weight and serum leptin in subjects with type 2 diabetes mellitus
The Journal of Nutrition; 1/1/2003; Belury, Martha A; Mahon, Annie; Banni, Sebastiano; 787 words
; The Conjugated Linoleic Acid (CLA) Isomer, t1Oc12-CLA, Is Inversely Associated with ... with Type 2 Diabetes Mellitus'2 ABSTRACT Isomers of conjugated linoleic acid (CLA) are ... either a supplement containing mixed CLA isomers (CLA-mix; 8.0 g daily, 76% pure CLA; n ...
Read more
|
|
Effect of Abomasal Infusions of Geometric Isomers of 10,12 Conjugated Linoleic Acid on Milk Fat Synthesis in Dairy Cows
Lipids; 8/1/2005; Sæbø, Asgeir; Sæbø, Per-Christian; Griinari, J Mikko; Shingfield, Kevin J; 787 words
; ABSTRACT: The frans-10,cis-12 isomer of conjugated linoleic acid (CLA) decreases ... current experiment, the effects of geometric isomers of 10,12 CLA on milk fat synthesis were ... or a mixture of predominantly 10,12 isomers containing (g/100 g) trans-10,cis-12 ...
Read more
|
|
Isomers of Conjugated Linoleic Acid Differ in Their Effects on Angiogenesis and Survival of Mouse Mammary Adipose Vasculature1
The Journal of Nutrition; 2/1/2004; Masso-Welch, Patricia A; Zangani, Danilo; Ip, Clement; Vaughan, Mary M; Et al; 787 words
; ... the mouse mammary gland. To determine which isomer mediates the antiangiogenic effects of CLA ... supplemented with 5 or 10 g/kg c9,t11- or t10,c12-CLA isomers were compared in CD2F1Cr mice. Both isomers inhibited functional vascularization of a matrigel ...
Read more
|
|
Purer single-isomer bronchodilator approved for bronchospasm
Drug Topics; 4/19/1999; Portyansky, Elena; 486 words
; ... into improved versions by separating out impure isomers and creating single-isomer agents. One drug that went back to the drawing ... racemic albuterol, an equal mixture of (R) and (S) isomers. The resultant improved chemical entity (ICE) is ...
Read more
|
|
Conjugated Linoleic Acid Alters Global Gene Expression in Human Intestinal-Like Caco-2 Cells in an Isomer-Specific Manner1-3
The Journal of Nutrition; 11/1/2007; Murphy, Eileen F; Hooiveld, Guido J; Muller, Michael; Calogero, Raffaele A; Cashman, Kevin D; 787 words
; ... Conjugated linoleic acid (CLA) exhibits isomer-specific effects on transepithelial calcium ... the molecular mechanisms underlying such isomer-specific effects. Caco-2 cells were treated ... a mixture of positional and geometric isomers of linoleic acid with conjugated double ...
Read more
|
|
Cis-9, Trans-11 and Trans-10, Cis-12 Conjugated Linoleic Acid Isomers Do Not Modify Body Composition in Adult Sedentary or Exercised Rats1
The Journal of Nutrition; 9/1/2004; Mirand, Philippe Patureau; Arnal-Bagnard, Marie-Agnès; Mosoni, Laurent; Faulconnier, Yannick; Et al; 787 words
; ABSTRACT Dietary CLA isomers were shown to reduce adipose tissues ... whether these effects depend on the isomer fed, on physical activity, or on the ... either no CLA, the cis-9, trans-11 CLA isomer (10 g/kg), the trans-10, cis-12 CLA ...
Read more
|
|
Single-isomer version of albuterol promises more potent bronchodilation
Formulary; 7/1/1998; Anonymous; 439 words
; Levalbuterol, the experimental single-isomer version of the widely prescribed bronchodilator ... albuterol"-is a 5050 combination of two isomers: (R)albuterol (levalbuterol) and (S)-albuterol ... metabolism between the two agents. "The (S)-isomer [found only in racemic albuterol] is metabolized ...
Read more
|
|
Adenoma growth stimulation by the trans-10, cis-12 isomer of conjugated linoleic acid (CLA) is associated with changes in mucosal NF-[kappa]B and cyclin D1 protein levels in the min mouse1,2
The Journal of Nutrition; 6/1/2003; Rajakangas, Johanna; Basu, Samar; Salminen, Irma; Mutanen, Marja; 787 words
; ... to describe the different conjugated isomers of linoleic acid. CLA has been found ... still inconclusive. In this study, the isomer-specific effects of the c/s-9, trans-11 and trans-10, cis-12 CLA isomers were investigated in the Min mouse model ...
Read more
|
|
Duodenal and milk trans octadecenoic acid and conjugated linoleic acid (CLA) isomers indicate that postabsorptive synthesis is the predominant source of cis-9-containing CLA...
The Journal of Nutrition; 6/1/2002; Piperova, Liliana S; Sampugna, Joseph; Teter, Beverly B; Kalscheur, Kenneth F; Et al; 787 words
; ... were analyzed to compare the content and isomer distribution of conjugated linoleic acids ... replaced trans-11-18:1 as the major 18:1 isomer. Milk CLA secretion (7.2-9.1 g/d) was ... of ruminally derived tFA. For other CLA isomers, duodenal flow was always greater than ...
Read more
|
|
Intra-individual comparison of 3(R)-BMIPP and 3(S)-BMIPP isomers in humans
The Journal of Nuclear Medicine; 10/1/1998; Caveliers, Vicky; Franken, Philippe R; Lin, Qun; Mokler, Florian T; Et al; 787 words
; ... imaging with SPECT. Recently, the 3(R)-BMIPP isomer showed a 20%-25% higher myocardial uptake ... 123-labeled 3(R)-BMIPP and 3(S)-BMIPP isomers were injected at rest, on two separate ... ns) for the 3(R)-BMIPP and 3(S)-BMIPP isomers, respectively. Liver activity averaged ...
Read more
|