hypertrophy

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hypertrophy

The Columbia Encyclopedia, Sixth Edition | 2008 | The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press. (Hide copyright information) Copyright

hypertrophy , enlargement of a tissue or organ of the body resulting from an increase in the size of its cells. Such growth accompanies an increase in the functioning of the tissue. In normal physiology the growth in size of muscles (e.g., in an athlete as a result of increased exercise) and also the enlargement of a uterus in pregnancy are caused by hypertrophy of muscle cells. In pathology the thickening of the heart muscle from overstrain, as in hypertension (high blood pressure), is the result of hypertrophy. An organ subjected to extra work (e.g., the one kidney left to function after surgical removal of the other) usually compensates by enlarging; in such cases hyperplasia, an increase in the number of cells, generally accompanies hypertrophy.

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hypertrophy

A Dictionary of Nursing | 2008 | © A Dictionary of Nursing 2008, originally published by Oxford University Press 2008. (Hide copyright information) Copyright

hypertrophy (hypertrophia) (hy-per-trŏ-fi) n. increase in the size of a tissue or organ brought about by the enlargement of its cells rather than by cell multiplication. See also (hypertrophic) cardiomyopathy. Compare hyperplasia, neoplasia.
hypertrophic adj.

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hypertrophy

A Dictionary of Biology | 2004 | © A Dictionary of Biology 2004, originally published by Oxford University Press 2004. (Hide copyright information) Copyright

hypertrophy An increase in the size of a tissue or organ due to an increase in the size of its component cells. Hypertrophy often occurs in response to an increased workload in an organ, which may result from malfunction or disease. Compare hyperplasia.

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