August von Wassermann

August von Wassermann , 1866-1925, German physician and bacteriologist. In Berlin he was director of the department of experimental therapy and serum research (1906-13) at Koch Institute and director of experimental therapy (from 1913) at the Kaiser Wilhelm Institute. In addition to developing inoculations against cholera, typhoid, and tetanus, he devised the Wassermann test (1906), used in the diagnosis of syphilis. A positive reaction when the blood or spinal fluid of the patient is tested indicates the presence of antibodies formed as a result of infection with syphilis (even though symptoms of the disease may not be observable at the time). A few other diseases, however (such as leprosy), also sometimes produce a positive Wassermann reaction.

Wassermann reaction (wass-er-măn) n. formerly, the most commonly used test for the diagnosis of syphilis. A sample of the patient's blood is examined for the presence of antibodies to Treponema pallidum. [ A. P. von Wassermann (1866–1925), German bacteriologist]