Addisons disease

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Addison's disease

The Columbia Encyclopedia, Sixth Edition | 2008 | The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press. (Hide copyright information) Copyright

Addison's disease [for Thomas Addison ], progressive disease brought about by atrophy of the outer layer, or cortex, of the adrenal gland ; it is also called chronic adrenocortical insufficiency. The deterioration of this tissue causes a decrease in the secretion of steroid hormones, many of which are necessary for the maintenance of life. In many cases the cause of the wasting process is not known; in others the predominant cause is the formation and infiltration of tumors, inflammatory disease, or surgery. Symptoms are increasing weakness, abnormal pigmentation of the skin and mucous membranes, weight loss, low blood pressure, dehydration, and gastrointestinal upsets. Secondary Addison's disease is most commonly caused by acute withdrawal of steroids. Once considered inevitably fatal, Addison's disease can now be treated with injections of adrenocortical hormones.

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chromatosis

A Dictionary of Nursing | 2008 | © A Dictionary of Nursing 2008, originally published by Oxford University Press 2008. (Hide copyright information) Copyright

chromatosis (kroh-mă-toh-sis) n. abnormal pigmentation of the skin, as occurs in Addison's disease.

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"chromatosis." A Dictionary of Nursing. Oxford University Press. 2008. Encyclopedia.com. 11 Nov. 2009 <http://www.encyclopedia.com>.

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(10/19/2008 8:40:00 PM)