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phase I metabolism

phase I metabolism The first stage in the conversion of a foreign compound, such as a drug or toxin, into a form that can be eliminated by the body. Common reactions during this phase are oxidation, reduction, and hydrolysis; the resulting metabolites are chemically more reactive than the parent compound, enabling them to undergo the reactions of the second stage (see phase II metabolism).

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"phase I metabolism." A Dictionary of Biology. . Encyclopedia.com. 17 Aug. 2017 <http://www.encyclopedia.com>.

"phase I metabolism." A Dictionary of Biology. . Encyclopedia.com. (August 17, 2017). http://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/phase-i-metabolism

"phase I metabolism." A Dictionary of Biology. . Retrieved August 17, 2017 from Encyclopedia.com: http://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/phase-i-metabolism

phase I metabolism

phase I metabolism The first phase of metabolism of foreign compounds (xenobiotics), involving metabolic activation. Generally regarded as detoxication reactions, but may in fact convert inactive precursors into metabolically active compounds, and involved in activation of precursors to carcinogens.

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"phase I metabolism." A Dictionary of Food and Nutrition. . Encyclopedia.com. 17 Aug. 2017 <http://www.encyclopedia.com>.

"phase I metabolism." A Dictionary of Food and Nutrition. . Encyclopedia.com. (August 17, 2017). http://www.encyclopedia.com/education/dictionaries-thesauruses-pictures-and-press-releases/phase-i-metabolism

"phase I metabolism." A Dictionary of Food and Nutrition. . Retrieved August 17, 2017 from Encyclopedia.com: http://www.encyclopedia.com/education/dictionaries-thesauruses-pictures-and-press-releases/phase-i-metabolism