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Harvey Williams Cushing

Harvey Williams Cushing

The American neurosurgeon Harvey Williams Cushing (1869-1939) developed operative techniques that made brain surgery feasible.

Harvey Cushing was born on April 8, 1869, in Cleveland, Ohio. He graduated from Yale University in 1891 and received a medical degree in 1895 from Harvard Medical School. After a year's internship at Massachusetts General Hospital he went to Johns Hopkins, where he was William Halsted's resident in surgery. From Halsted he learned meticulous surgical technique.

During a trip to Europe in 1900 Cushing worked with some of Europe's leading surgeons and physiologists, including Charles Scott Sherrington, Theodore Kocher, and Hugo Kronecker. They directed his attention to neurosurgery, to which he devoted the rest of his life. Shortly after his return to Johns Hopkins he was made associate professor of surgery. In 1902 he married Katharine Crowell.

In 1907 Cushing began studies of the pituitary gland. He unraveled many of the disorders affecting the gland and showed that a surgical approach to the pituitary was possible. In 1912 The Pituitary Body and Its Disorders was published. In that same year he accepted the Moseley professorship of surgery at Harvard and an appointment as surgeon in chief at Peter Bent Brigham Hospital in Boston. During World War I he served in France as director of Base Hospital No. 5. His wartime experiences formed the basis of a book, From a Surgeon's Journal (1936). Cushing's active affiliation with Harvard continued until 1932, when he was named professor emeritus. The following year he accepted the Sterling professorship of neurology at Yale.

Throughout his career Cushing studied brain tumors and published many important books on the subject, including: Tumours of the Nervus Acusticus and the Syndrome of the Cerebellopontile (1917); A Classification of the Tumours of the Glioma (1926), with P. Bailey; Tumours Arising from the Blood Vessels of the Brain: Angiomatous Malformations and Hemangioblastomas (1928), with Bailey; Intracranial Tumours (1932); and Meningiomas: Their Classification, Regional Behavior, Life History, and Surgical End Results (1938). He published numerous historical essays, and his biography of Sir William Osler (1925) received the Pulitzer Prize in 1926.

Cushing's use of local anesthesia in brain surgery was an outstanding achievement, as were his many special surgical techniques. In 1911 he introduced special sutures to control the severe bleeding that accompanies brain surgery and often made it impossible.

In 1937 Cushing accepted a position as director of studies in the history of medicine at Yale. He guided the development of a historical library to which he left his own excellent collection of historical books. He was especially interested in Andreas Vesalius, the 16th-century anatomist, and was at work on the Bio-Bibliography of Vesalius at the time of his death, on Oct. 7, 1939. The work was completed by his friends and published in 1943.

Further Reading

The definitive biography of Cushing is John F. Fulton, Harvey Cushing (1946). A shorter biography for the general reader is Elizabeth Harriet Thomson, Harvey Cushing: Surgeon, Author, Artist (1950). On the occasion of Cushing's seventieth birthday, in 1939, A Bibliography of the Writings of Harvey Cushing was published by the Harvey Cushing Society.

Additional Sources

Fulton, John F. (John Farquhar), Harvey Cushing, a biography, New York: Arno Press, 1980, 1946. □

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Cushing, Harvey Williams

Harvey Williams Cushing, 1869–1939, American neurosurgeon, b. Cleveland, B.A. Yale, 1891, M.D. Harvard, 1895. Associated with Johns Hopkins (1896–1912), Harvard (1912–32), and Yale (1933–37), he was noted for his great contributions to brain surgery and also as a teacher and an author. For his life of Sir William Osler he won the 1925 Pulitzer Prize in Biography. Among his other works are a famous treatise on the pituitary body, as well as Tumors of the Nervus Acusticus (1917), Intracranial Tumours (1932), and the autobiographical From a Surgeon's Journal, 1915–1918 (1936).

See biographies by J. F. Fulton (1946) and E. H. Thomson (1950).



Cushing's disease was first described by him. It is a disorder attributed to hyperactivity of the cortex of the adrenal glands and affects women more than men. The symptoms include obesity (moonface, an accumulation of fat at the back of the neck called buffalo hump, and abdominal protrusion), hypertension, hirsutism, and easy bruisability. Treatment is by X-ray therapy if the pituitary body is involved or by surgical removal of one or both adrenal glands.

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Cushing, Harvey

Cushing, Harvey (1869–1939) US surgeon. His pioneering techniques for surgery on the brain and spinal cord helped advance neurosurgery. He first described the syndrome produced by over-secretion of adrenal hormones that is now known as ‘Cushing's syndrome’. It is characterized by weight-gain in the face and trunk, high blood pressure, excessive growth of facial and body hair, and diabetes-like effects.

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