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gramicidin

gramicidin (grăm´Ĭsīd´ən), antibiotic obtained from the bacterial species Bacillus brevis, which is found in soil. Gramicidin is particularly effective against gram-positive bacteria (see Gram's stain). Because the drug is highly toxic, it cannot be administered internally and so is used only on the skin as a lotion or ointment. It is used primarily in the treatment of infected surface wounds, and in eye, nose, and throat infections. In 1939 the American microbiologist René Dubos isolated the substance tyrothricin and later showed that it was composed of two substances, gramicidin and tyrocidine. These were the first antibiotics to be manufactured commercially.

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"gramicidin." The Columbia Encyclopedia, 6th ed.. . Encyclopedia.com. 23 Aug. 2017 <http://www.encyclopedia.com>.

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"gramicidin." The Columbia Encyclopedia, 6th ed.. . Retrieved August 23, 2017 from Encyclopedia.com: http://www.encyclopedia.com/reference/encyclopedias-almanacs-transcripts-and-maps/gramicidin

gramicidin

gramicidin (gram-i-sy-din) n. an antibiotic that acts against a wide range of bacteria. It is used in combination with other antibacterial drugs or steroids in topical preparations for the treatment of skin, ear, and eye infections.

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"gramicidin." A Dictionary of Nursing. . Encyclopedia.com. 23 Aug. 2017 <http://www.encyclopedia.com>.

"gramicidin." A Dictionary of Nursing. . Encyclopedia.com. (August 23, 2017). http://www.encyclopedia.com/caregiving/dictionaries-thesauruses-pictures-and-press-releases/gramicidin

"gramicidin." A Dictionary of Nursing. . Retrieved August 23, 2017 from Encyclopedia.com: http://www.encyclopedia.com/caregiving/dictionaries-thesauruses-pictures-and-press-releases/gramicidin