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aldosterone
aldosterone
aldosterone (al-dos-ter-ohn) n. a steroid hormone (see
corticosteroid) that is synthesized and released by the adrenal cortex and acts on the kidney to regulate salt (potassium and sodium) and water balance.
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Aldosterone Receptor Antagonists in the Medical Management of Chronic Heart Failure
Magazine article from: Mayo Clinic Proceedings; 12/1/2005; ; 700+ words
; The benefits of aldosterone receptor antagonists (spironolactone...proposed mechanisms of action of aldosterone antagonists are (1) inhibition...Like many hormone receptors, the aldosterone receptor can be either nuclear or...
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Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial [Na.sup.+] channel [alpha].(Research article)
Magazine article from: Journal of Clinical Investigation; 3/1/2007; ; 700+ words
; Aldosterone plays a major role in the regulation...cardiovascular and renal diseases. Many aldosterone-regulated genes--including that...as the release of this repression by aldosterone treatment. Here we provide evidence...
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Does the aldosterone: renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study.(Study protocol)
Magazine article from: BMC Cardiovascular Disorders; 5/9/2007; ; 700+ words
; ...antihypertensive control would be to target aldosterone antagonists towards patients in whom...characterised by excessive excretion of aldosterone with concomitant suppression of renin...with hypertension. However, neither aldosterone excretion nor plasma renin activity...
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Validity of the aldosterone-renin ratio used to screen for primary aldosteronism
Magazine article from: Mayo Clinic Proceedings; 9/1/2001; ; 700+ words
; ...whether the calculated ratio of plasma aldosterone concentration (PAC) to plasma renin...independent measure of circulating aldosterone that is suitable to judge whether PAC...d). Results: The variation in the aldosterone-renin ratio was strongly and inversely...
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Non-genomic effects of aldosterone on intracellular ion regulation and cell volume in rat ventricular myocytes.
Magazine article from: Canadian Journal of Physiology and Pharmacology; 2/1/2007; ; 700+ words
; Abstract: Aldosterone has non-genomic effects that express...However, it is still undefined whether aldosterone actually alters intracellular ion...clarify the non-genomic effects of aldosterone, we measured [[[Na.sup...
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Automated Chemiluminescence-Immunoassay for Aldosterone during Dynamic Testing: Comparison to Radioimmunoassays with and without Extraction Steps
Magazine article from: Clinical Chemistry; 9/1/2006; ; 700+ words
; Background: Measurements of aldosterone have become more common since...sampling. In all blood samples, aldosterone concentration was measured by...available RIAs without extraction (Aldosterone Maia, Adaltis; Active Aldosterone...
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Cardiovascular benefits of aldosterone receptor antagonists
Magazine article from: Climacteric; 10/1/2003; ; 700+ words
; ...in addition to the classic effects of aldosterone on sodium retention, blood volume, blood pressure and potassium homeostasis, aldosterone is involved in fibrotic end-organ...myocardial infarction by the addition of an aldosterone receptor antagonist to standard therapy...
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Aldosterone is relevant for determination of left ventricular mass.
Newspaper article from: Heart Disease Weekly; 4/20/2003; 700 words
; ...NewsRx.com & NewsRx.net) -- Aldosterone is relevant for determination of left...experimental studies, the importance of aldosterone for the development of left ventricular...mode echocardiography), urinary aldosterone concentration, and the response of...
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Plasma Aldosterone Assays: Comparison between Chemiluminescence-Based and RIA Methods
Magazine article from: Clinical Chemistry; 7/1/2006; ; 700+ words
; To the Editor: Measurement of plasma aldosterone is increasingly required in clinical practice because...alternatives to traditional RIAs for hormones such as aldosterone. We compared aldosterone results obtained with a new CL method (Nichols...
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Aldosterone-synthase overexpression can be studied in mice hearts.
Newspaper article from: Biotech Week; 7/28/2004; 616 words
; ...com & NewsRx.net) -- Anti-aldosterone treatment may block cardiac aldosterone action in heart failure. According to recent...Clinical observations indicate that elevated aldosterone impairs cardiovascular function. The mechanisms...
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Aldosterone Assay
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
Aldosterone Assay Definition This test measures the levels of aldosterone, a hormone produced by the outer part (cortex...organs which sit one on top of each of the kidneys. Aldosterone regulates the amounts of sodium and potassium in...
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aldosterone
Book article from: The Columbia Encyclopedia, Sixth Edition
aldosterone , steroid secreted by the cortex of...regulating the body's electrolyte balance. Aldosterone acts directly on the kidney to decrease...potassium-ion excretion. The secretion of aldosterone appears to be regulated by two mechanisms...
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Hyperaldosteronism
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
...defined by the body's overproduction of aldosterone, a hormone that controls sodium and...often begins with a tumor that produces aldosterone. In fact, approximately 60-70...from tumors in the adrenal gland area. Aldosterone is normally produced by the adrenal...
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Plasma Renin Activity
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
...further evaluate a diagnosis of excess aldosterone, a hormone secreted by the adrenal...is called the renin-angiotensin-aldosterone cycle. This cycle includes the conversion...its action stimulates the release of aldosterone from an area of the adrenal glands called...
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adrenal glands
Book article from: The Oxford Companion to the Body
...of these regions produces the steroid aldosterone , while another steroid hormone, cortisol...converted into the steroid hormones. Aldosterone, by acting on the kidneys, controls...controls the blood pressure. The amount of aldosterone produced is controlled by other substances...
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