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uric acid
uric acid
uric acid The end product of purine breakdown in most mammals, birds, terrestrial reptiles, and insects and also (except in mammals; see
urea) the major form in which metabolic nitrogen is excreted. Being fairly insoluble, uric acid can be expelled in solid form, which conserves valuable water in arid environments. The accumulation of uric acid in the synovial fluid of joints causes gout.
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Uric Acid, Type 2 Diabetes, and Cardiovascular Diseases: Fueling the Common Soil Hypothesis?
Magazine article from: Clinical Chemistry; 2/1/2008; ; 700+ words
; Uric acid is the final oxidation product...diseases, and most notably uric acid is causally involved in...across extreme quintiles of uric acid in multivariable analyses...that part of the effect of uric acid on the incidence of diabetes...
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Preparation of Uric Acid Standard Stock Solution
Magazine article from: Clinical Chemistry; 11/1/2006; ; 673 words
; To the Editor: For measurement of uric acid in serum, calibrators of known concentration...be prepared in a suitable solvent. Uric acid is virtually insoluble in water...hydroxide as the solvent for dissolving uric acid at a molar ratio of ammonium hydroxide...
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Associations of uric acid with polymorphisms in the [delta]-aminolevulinic acid dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workers.(Research)
Magazine article from: Environmental Health Perspectives; 11/1/2005; ; 700+ words
; ...research suggests that uric acid may be nephrotoxic...associated with higher uric acid in those with the...lead exposure, uric acid, vitamin D receptor...and increased uric acid levels (Lin et al...literature suggests that uric acid may be nephrotoxic...
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Changes in urinary uric acid excretion in obstructive sleep apnea before and after therapy with nasal continuous positive airway pressure.
Magazine article from: Chest; 6/1/1998; ; 700+ words
; ...To assess the utility of urinary uric acid excretion as a marker of nocturnal...the purine catabolic end product, uric acid.[1] Elevated levels of ATP degradation...of an overnight change in urinary uric acid:creatinine ratio as a marker of...
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Uric Acid May Help Reduce Effects of Spinal Cord Injury, Jefferson Researchers Find.
News Wire article from: Ascribe Higher Education News Service; 2/14/2005; 700+ words
; ...Increasing levels of uric acid, a metabolic breakdown...rats that were given uric acid. "The injury causes a...two or three joints. The uric acid-treated rats recovered...feasible to give someone uric acid immediately and raise levels...
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Perchloric Acid Treatment To Stabilize Uric Acid Concentrations in Blood Samples of Patients Receiving Uric Acid Oxidase (Rasburicase) Therapy
Magazine article from: Clinical Chemistry; 2/1/2007; ; 700+ words
; ...the Editor: Sample handling requirements for uric acid analysis during recombinant uric acid oxidase (rasburicase, Sanofi-Synthelabo...Following the manufacturer's instructions, uric acid concentration was 83 mol/L, compared to 95...
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Associations among lead dose biomarkers, uric acid, and renal function in Korean lead workers.(Research)
Magazine article from: Environmental Health Perspectives; 1/1/2005; ; 700+ words
; ...Recent research suggests that both uric acid and lead may be nephrotoxic at lower...Fructuoso et al. 2002; Vaziri 2002). Uric acid is also a nephrotoxicant, and increasing...lead biomarkers were associated with uric acid and whether uric acid levels were...
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Does woman patient's raised uric acid require treatment?
Newspaper article from: Pulse; 5/19/2003; 700+ words
; ...are normal except she had a raised uric acid at 620 micro mol/l. What do you...is an important factor in raised uric acid, a `crash diet' to reduce weight...likely with increasing levels of uric acid * Most important predictor of...
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High serum uric acid linked to atherosclerosis.(CARDIOVASCULAR MEDICINE)
Magazine article from: Family Practice News; 8/1/2009; ; 700+ words
; ...asymptomatic adults with elevated serum uric acid levels had a significantly increased...into quartiles based on their serum uric acid levels. The highest quartile level...10 had gout, although with serum uric acid levels this high many more would...
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Sample Preparation in Patients Receiving Uric Acid Oxidase (Rasburicase) Therapy
Magazine article from: Clinical Chemistry; 8/1/2003; ; 700+ words
; ...patient who received the recombinant uric acid oxidase Rasburicase (Sanofi-Synthelabo...sample handling requirements for uric acid analysis. Rasburicase is a...medications may cause artefactually low uric acid concentrations, as documented in...
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Uric Acid Tests
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
...measure the level of kidney functioning. Uric acid is a waste product that results from the breakdown of purine, a nucleic acid. (Nucleic acids are the building blocks of DNA.) Uric acid is made in the liver and excreted by the...
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uric acid
Book article from: The Columbia Encyclopedia, Sixth Edition
uric acid , white, odorless, tasteless...to form purines and finally uric acid; these so-called uricotelic...normal human blood. The pure acid is obtained from guano and...which is then evaporated. If uric acid is present, murexide...
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Lactic Acid
Encyclopedia entry from: The Gale Encyclopedia of Science
...the bloodstream and the lactic acid is converted to carbon dioxide...which are exhaled. If lactic acid levels in the bloodstream rise...x2014; combinations of acids, salts, and bases that maintain...metabolize, or break down, lactic acid is decreased significantly by...can also lead to a buildup ...
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Anti-Hyperuricemic Drugs
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
...hyperuricemia, the state of having too much uric acid in the blood. Purpose Anti-hyperuricemic drugs decrease the levels of uric acid in the blood, either by increasing...allopurinol decreases the amount of uric acid that is produced (and may help prevent...
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Gout Drugs
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed.
...Purpose Gout is a disease in which uric acid, a waste product that normally passes...wine, may increase the amount of uric acid in the body and may interfere with...conditions that result from excess uric acid) may need to limit the amount...
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