proximal convoluted tubule

A Dictionary of Biology | 2004 | 557 words | Copyright

proximal convoluted tubule (first convoluted tubule) The section of a nephron situated between Bowman's capsule and the loop of Henle in the vertebrate kidney. Reabsorption of salt, water, and glucose from the glomerular filtrate occurs in this tubule; at the same time certain substances, including uric acid and drug metabolites, are actively transferred from the blood capillaries into the tubule. Both activities are facilitated by finger-like projections (see brush border) on the inner surface of the tubule, which increase its effective surface area.

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