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notochord
notochord
notochord An elastic skeletal rod lying lengthwise beneath the nerve cord and above the alimentary canal in the embryos or adults of all chordate animals (see
Chordata). Its function is to strengthen and support the body and act as a protagonist for the muscles. It is found in both adult and larval lancelets but in adult vertebrates it is largely replaced by the
vertebral column.
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Continued growth and cell proliferation into adulthood in the notochord of the appendicularian Oikopleura dioica.(Author abstract)
Magazine article from: The Biological Bulletin; 2/1/2008; ; 700+ words
; ...region and a motile tail containing a notochord and a dorsal nerve cord (Katz, 1983...loss of tail structures, including the notochord. The salps and doliolids (Thaliacea...undergo a metamorphosis through which the notochord (if initially formed at all) is lost...
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A high-affinity hemoglobin is expressed in the notochord of amphioxus, Branchiostoma californiense.
Magazine article from: The Biological Bulletin; 12/1/1998; ; 700+ words
; ...occurs at 500 nm in the in situ notochord and in vitro myotome spectra...for crude protein extract from notochords is shown in Figure 2A and from...protein peaks are evident. For both notochord and myotome extracts, the first...
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The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish.(Research article)
Magazine article from: BMC Developmental Biology; 4/17/2008; ; 700+ words
; ...where U0126 treatment blocked differentiation of mesenchyme, secondary muscle and neural tissues and formation of the notochord (NC) [27, 28, 29]. The NC serves as the most important skeletal structure in lower chordates and plays an essential...
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A Novel Murine Gene, Sickle tail, Linked to the Danforth's short tail Locus, Is Required for Normal Development of the Intervertebral Disc
Magazine article from: Genetics; 1/1/2006; ; 700+ words
; ...of a reporter gene was detected in the notochord during embryogenesis and in the nucleus...the third intron of the Skt gene. THE notochord is an integral component of the axial...CHIANG et eZ.1996). In addition, the notochord has major roles in vertebral column formation...
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Mechanisms of specification in ascidian embryos.(Genetic Regulatory Networks in Embryogenesis and Evolution)
Magazine article from: The Biological Bulletin; 12/1/1998; ; 700+ words
; ...nerve cord, endoderm, mesenchyme, notochord, and muscle (2). The lineage of these...initiation site (9). Specification of notochord Recent studies have revealed an important...tissue. Differentiation of ascidian notochord cells is induced during the early phase...
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New developmental biology study findings have been reported by T.A. Hawkins and co-researchers.
Newspaper article from: Life Science Weekly; 8/12/2008; 700+ words
; "Key molecules involved in notochord differentiation and function have...potential role for Mek1/2 during notochord development by using the small molecule...tail and an abnormal, undulated notochord. Using morphological analysis...
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STUDY SHEDS LIGHT ON NERVE DEFECTS
News Wire article from: United Press International; 9/9/1998; 614 words
; ...questions about the classic model of the notochord, a vital rod-like structure that precedes...traditional understanding has been that the notochord signals neural cells to induce the formation...cord. But new data cast doubt on the notochord's role. In the latest report, in...
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Research conducted at M. Anjomshoa and co-authors has provided new information about stem cell research.
Newspaper article from: Biotech Week; 4/22/2009; 700+ words
; ...coculture embryonic notochord model in vitro...bead-encapsulated notochords isolated from Hamburger...embryos. The use of notochord alone was not able...effectiveness of embryonic notochord coculture in providing...Cells with Chicken Notochords. Stem Cells and Development...
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New gastroenterology study results from Cornell University described.
Newspaper article from: Gastroenterology Week; 12/7/2009; 700+ words
; ...research from the United States, "The notochord is a defining feature of the chordate...transcription factors is required for notochord development." "However, studies on...complicated by the limited knowledge of notochord genes and cis-regulatory modules...
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Evolutionary implications of FGF and distal-less expressions during proximal-distal axis formation in the ampulla of a direct-developing ascidian, Molgula pacifica. (fibroblast growth factor)
Magazine article from: The Biological Bulletin; 6/1/1998; ; 700+ words
; ...in ascidian development (11). When notochord progenitor cells were isolated from embryos...descendants of these cells expressed a notochord-specific protein, termed "Not-1...that FGF2 receptors may be present in notochord cells of indirect-developing embryos...
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notochord
Book article from: The Columbia Encyclopedia, Sixth Edition
notochord , in biology, supporting rod running...a firm connective tissue sheath, the notochord lies between the neural tube (spinal...subphyla is based on the structure of the notochord and the time of life in which it is present...
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Chordata
Book article from: The Columbia Encyclopedia, Sixth Edition
...Chordata , phylum of animals having a notochord, or dorsal stiffening rod, as the chief...least during early development are: the notochord, composed of gelatinous tissue and bound...or spinal cord), located above the notochord; and gill slits leading into the pharynx...
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Chordates
Encyclopedia entry from: The Gale Encyclopedia of Science
...and Vertebrata. Urochordates have a notochord (a hollow dorsal nerve cord) while...stage. Cephalochordates have both a notochord and a nerve cord but do not have vertebrae...chordates is a structure known as the notochord. This is a rod-like flexible structure...
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Growth and Differentiation of the Nervous System
Book article from: Animal Sciences
...but only those cells that are adjacent to the notochord do so. The notochord is an elongated, tubelike structure that runs...still only a sack of cells (gastrula stage), the notochord forms and releases chemicals onto the overlying...
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lancelet
Book article from: The Columbia Encyclopedia, Sixth Edition
...tunicate ). The lancelet has a dorsal notochord, or stiffening rod, extending from...characteristic pointed shape. It retains the notochord as the major skeletal support throughout life; in vertebrates the notochord is surrounded and usually replaced...
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