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histone
histone
histone Any of a group of water-soluble proteins found in association with the
DNA of plant and animal chromosomes. They contain a large proportion of the basic (positively charged) amino acids lysine, arginine, and histidine. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity (see
chromatin). Histones do not occur in vertebrate sperm cells (see
protamine) or in bacteria, although a very similar protein has been found in the genome of the archaebacterium Thermoplasma.
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Histone gene expression and histone mRNA 3' end structure in Caenorhabditis elegans.(Research article)(ribonucleic acid)(Clinical report)
Magazine article from: BMC Molecular Biology; 6/14/2007; ; 700+ words
; ...structure. Specialised histones, termed replacement variant histones, define specialised...replacement variant histone genes is not linked...the alignment of histone gene 3'UTRs is...UTR elements of histones H2A, H2B, H3 and...
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Is histone loss a common feature of DNA metabolism regulation? (1).
Magazine article from: Biochemistry and Cell Biology; 8/1/2006; ; 700+ words
; ...covalently modifying histones, by shifting nucleosomes...by changing the histone composition of nucleosomes...modifications/echanges des histones et le deplacement...chromatine, nucleosome, histone, demethylation...nucleosomes can exchange histones from the nucleosome...composition of the ...
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Histone acetylation: truth of consequences?(Report)
Magazine article from: Biochemistry and Cell Biology; 2/1/2009; ; 700+ words
; ...was packaged with histones that were post-translationally...field today: why is histone acetylation there...around an octamer of histones containing 2 copies of histones H2A, H2B, H3, and...1988). Each core histone has 2 domains: a...
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Histone H3K4 demethylases are essential in development and differentiation (1).(MINIREVIEW / MINISYNTHESE)(Report)
Magazine article from: Biochemistry and Cell Biology; 8/1/2007; ; 700+ words
; ...Key words: JARID1, histone methylation, JmjC domain...La methylation des histones sur les residus lysine...de la lysine 4 de l'histone H3 semble etre particulie...JARID1, methylation d'histones, domaine JmjC, H3K4me3...and distribution of histone methylation have been...
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Histones Receive New Respect.
Newspaper article from: Genomics & Genetics Weekly; 8/24/2001; 700+ words
; ...around small blobs of histones (the beads) at regular...researchers believed that histones played a passive role...who remained true to histone research are basking...chromosome structure by histones may activate or silence...between two varieties of histone have dramatic effects...
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HISTONE DEACETYLASE19 Is Involved in Jasmonic Acid and Ethylene Signaling of Pathogen Response in Arabidopsis
Magazine article from: Plant Cell; 4/1/2005; ; 700+ words
; ...determined by the action of histone acetyltransferases and histone deacetylases (HDAC). Acetylation of the histones is often associated...whereas deacetylation of histones is correlated with...identified a series of histone acetyltransferasecoactivator...
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Histone Modifications and Expression of Light-Regulated Genes in Arabidopsis Are Cooperatively Influenced by Changing Light Conditions1[W][OA]
Magazine article from: Plant Physiology; 8/1/2008; ; 700+ words
; ...effects of light regulation on four selected histone modifications (H3K4me3, H3K9ac, H3K9me2...H3K27me3) and the relationship of these histone modifications with the expression of representative...regulated genes. We observed that the histone modifications examined and gene transcription...
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Histone Binding Site of HCV Identified.
Newspaper article from: Hepatitis Weekly; 8/9/1999; 700+ words
; ...functions of the histones in vitro. HCV protein...exhibiting the mentioned histone binding activity...interaction with histones was defined by proteolytic...microsequencing and a specific histone binding assay...the interaction of histones with DNA was established...binding of DNA to ...
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STUDY: HISTONES CONTROL GENETIC ACTION
News Wire article from: United Press International; 8/9/2001; 700+ words
; ...International, "But histones govern the genes...second enzyme to modify a histone. In the study, researchers...also be able to harness histones to find cures for disease. Grewal said histones undoubtedly are part...Understanding the histone system and other epigenetic...
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Targeted histone acetylation and altered nuclease accessibility over short regions of the pea plastocyanin gene
Magazine article from: Plant Cell; 3/1/2001; ; 700+ words
; ...shoots. The acetylation states of histones associated with different regions...specific for acetylated or nonacetylated histone H3 or H4 tails, followed by polymerase...Moreover, hyperacetylation of both histones H3 and H4 was targeted to the enhancer...
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histone
Book article from: The Columbia Encyclopedia, Sixth Edition
histone , any of a class of protein molecules found...function in the transcription of DNA. The histones are rich in the amino acids arginine and...been greatly conserved during evolution, histone structures vary little in a wide range...
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histones
Book article from: A Dictionary of Food and Nutrition
histones Proteins rich in arginine and lysine, soluble in water but not dilute ammonia. They occur mainly in the cell nucleus and are concerned with the regulation of DNA .
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Chromosome, Eukaryotic
Book article from: Biology
...structure of individual histones to loosen the histone-DNA contacts, thereby...transcription is the histone acetyltransferases...terminal tails of histones. Acetylation of lysines...positive charge of the histone protein; since DNA...
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Gene Expression: Overview of Control
Book article from: Genetics
...chemical modification of the histone proteins to which the DNA...to the positively charged histones. By adding or removing chemical groups to the histones, this attraction can be...negatively charged groups to the histones, tends to open up the chromatin...
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chromatin
Book article from: A Dictionary of Biology
...consists of proteins (principally histones), DNA, and small amounts of RNA...DNA molecule is wrapped around the histones to form a series of linked globular...by reversible acetylation of the histones: the greater the degree of acetylation...
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