Research topic:Down syndrome

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Find more facts and information on our topic page about Down syndrome

Down's syndrome

A Dictionary of Biology | 2004 | © A Dictionary of Biology 2004, originally published by Oxford University Press 2004. (Hide copyright information) Copyright

Down's syndrome A congenital form of mental retardation due to a chromosome defect in which there are three copies of chromosome no. 21 instead of the usual two (see trisomy). The affected individual has a short broad face and slanted eyes (as in the Mongolian races), short fingers, and weak muscles. Down's syndrome can be detected before birth by amniocentesis. It is named after the British physician John Down (1828–96), who first studied the incidence of the disorder.

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