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pantothenic acid

A Dictionary of Food and Nutrition | 2005 | | © A Dictionary of Food and Nutrition 2005, originally published by Oxford University Press 2005. (Hide copyright information) Copyright

pantothenic acid A vitamin of the B complex with no numerical designation. Chemically, the β‐alanine derivative of pantoic acid. Required for the synthesis of coenzyme A (and hence essential for the metabolism of fats, carbohydrates, and amino acids) and of acyl carrier protein (and hence essential for the synthesis of fatty acids).

Dietary deficiency is unknown; it is widely distributed in all living cells, the best sources being liver, kidney, yeast, and fresh vegetables. Human requirements are not known with any certainty; the US/Canadian adequate intake is 5 mg/day.

Experimental deficiency signs in rats include greying of the hair (hence at one time known as the anti‐grey‐hair factor; there is no evidence that it affects greying of human hair with age). Experimental deficiency in human beings leads to fatigue, headache, muscle weakness, and gastro‐intestinal disturbances. See also burning foot syndrome.

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