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isoniazid
antivitamins
A Dictionary of Food and Nutrition
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2005
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© A Dictionary of Food and Nutrition 2005, originally published by Oxford University Press 2005. (Hide copyright information)
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antivitamins Substances that interfere with the normal metabolism or function of
vitamins, or destroy them. Dicoumarol in spoiled sweet clover antagonizes the function of
vitamin K, thiaminase in raw fish destroys
vitamin B1, the drug methotrexate antagonizes
folic acid metabolism (this is part of its mechanism of action in treating cancer), the drug isoniazid antagonizes the action of
vitamin B6.
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Isoniazid preventive therapy and risk for resistant tuberculosis.
Magazine article from: Emerging Infectious Diseases; 5/1/2006; ; 700+ words
; ...context of tuberculosis (TB) resurgence, isoniazid preventive therapy (IPT) is increasingly...concerns about the risk for development of isoniazid-resistant tuberculosis may hinder its...effect of primary IPT on the risk for isoniazid-resistant TB. Different definitions...
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Isoniazid toxicity: A treatable cause of status epilepticus
Magazine article from: Journal of Pediatric Neurology; 7/1/2009; ; 700+ words
; ...history of accidental ingestion of 13 tablets isoniazid-rifampicin (89 mg/kg isoniazid), 1 hr earlier, presented with generalized...phenobarbitone. Given in gram per gram amounts of the isoniazid ingested, intravenous pyridoxine (vitamin...
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Isoniazid- and ethambutol-induced psychosis.(Case Report)(Case study)
Magazine article from: Annals of Thoracic Medicine; 10/1/2008; ; 700+ words
; ...associated psychoses were caused by isoniazid (INH), with ethambutol (EMB)-induced...and had no further psychotic symptoms. Isoniazid (INH) is included in all drug regimens...with an initial 2 months of rifampicin, isoniazid, ethambutol, and pyrazinamide followed...
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Failure of isoniazid chemoprophylaxis during infliximab therapy.(LETTERS)(Letter to the editor)
Magazine article from: Emerging Infectious Diseases; 9/1/2007; ; 700+ words
; ...testing with purified protein derivative, isoniazid chemoprophylaxis was started 2 weeks...developed in the patient, caused by isoniazid-resistant Mycobacterium kansasii...the first documented case of failure of isoniazid prophylaxis due to the emergence of isoniazid...
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Epiroprim Plus Isoniazid Shows Strong Anti-M. tuberculosis Activity In Vitro.
Newspaper article from: Drug Week; 4/20/2001; 700+ words
; ...its own but may be a useful adjunctive therapy to isoniazid - even in isoniazid-resistant strains. In vitro studies show that...M. tuberculosis, including those resistant to isoniazid and rifampin, and those susceptible to one or...
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Detection of mutation in isoniazid-resistant Mycobacterium tuberculosis isolates from tuberculosis patients in Belarus.(Brief Communication)
Magazine article from: Indian Journal of Medical Microbiology; 4/1/2008; ; 700+ words
; ...from patients in Belarus. Forty two isoniazid-resistant isolates were identified...Standard PCR method for detection of isoniazid resistance associated mutations was performed...population.[sup] [6] Resistance to isoniazid is increasing in Belarus because 88...
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Pure red blood cell aplasia and isoniazid use.(LETTERS)(Clinical report)
Magazine article from: Emerging Infectious Diseases; 9/1/2007; ; 700+ words
; To the Editor: Isoniazid is a first-line drug in the treatment...include prevention as well as cure. Isoniazid is usually well tolerated, although...implicated (2), and few reports involving isoniazid have been published. We report a case...
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Seizures, Metabolic Acidosis and Coma Resulting from Acute Isoniazid Intoxication
Magazine article from: Anaesthesia and Intensive Care; 8/1/2005; ; 700+ words
; SUMMARY Isoniazid is an anti-tuberculosis drug, used...and prophylaxis of tuberculosis. Acute isoniazid intoxication is characterized by a clinical...in a dose equivalent to the amount of isoniazid ingested, is the only effective antidote...
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Isoniazid safe for liver transplant candidates.
Newspaper article from: TB & Outbreaks Week; 12/17/2002; 620 words
; ...writer - The potent antituberculosis agent isoniazid can be safely administered to patients...say. "Optimal timing of initiation of isoniazid chemoprophylaxis in liver transplant...Affairs Medical Center in Pittsburgh. Isoniazid therapy could be initiated during the...
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Exploration of cold extrusion for the preparation of enteric minitablets of isoniazid.(Research Paper)(Clinical report)
Magazine article from: Indian Journal of Pharmaceutical Sciences; 5/1/2008; ; 700+ words
; ...formulate the enteric minitablets of isoniazid by cold extrusion method. The minitablets were prepared using isoniazid, hydroxylpropylmethylcellulose phthalate...containing rifampicin powder and enteric isoniazid minitablets showed complete drug release...
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isoniazid
Book article from: The Columbia Encyclopedia, Sixth Edition
isoniazid , drug used to treat tuberculosis . Also known as isonicotinic acid hydrazide, isoniazid is the most effective antituberculosis...reaction to a tuberculin skin test, isoniazid is given alone. Side effects are seen...
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Gerhard Johannes Paul Domagk
Encyclopedia entry from: Encyclopedia of World Biography
...to the discovery in 1951, by Domagk and others, of the activity of isonicotinic acid hydrazide (isoniazid). It was found that in man isoniazid was most efficient when combined with streptomycin and PAS. Chemotherapy of Cancer For 30 years...
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tuberculosis
Book article from: The Columbia Encyclopedia, Sixth Edition
...prevention and for active cases is the antimicrobial drug isoniazid (INH), available since 1956. In infected individuals it...essentially untreatable. The combination drug rifater (rifampin, isoniazid, and pyrazinamide) has simplified drug administration...
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INH
Book article from: A Dictionary of Nursing
INH n. see isoniazid .
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hydrazine
Book article from: The Columbia Encyclopedia, Sixth Edition
...agricultural chemicals; in rubber curing and the manufacture of foam rubber and plastics; in soldering fluxes; and as a corrosion inhibitor in boiler feedwater. Isoniazid , a drug used in treatment of tuberculosis, is isonicotinic hydrazide.
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