foundation
foundation institution through which private wealth is contributed and distributed for public purpose. Foundations have existed since Greek and Roman times, when they honored deities. During the Middle Ages in Europe the church had many foundations, and in the Arab lands the waqf, or pious endowment, developed with the growth of Islam. In modern times European foundations, generally smaller than their U.S. counterparts, have been closely regulated by the state (e.g., the Nobel prizes; see Nobel, Alfred Bernhard ).
In the United States there were a few early foundations, notably those endowed by Benjamin Franklin in 1791 to provide funds for loans to "young married artificers of good character" and by James Smithson in 1846 for the establishment of the Smithsonian Institution ; however, it was not until after the Civil War that foundations developed rapidly. Social disintegration in the South and the establishment of early foundations such as the Peabody Education Fund and the John F. Slater Fund (both designed to provide educational opportunities for African Americans in the South) promoted the movement. The rapid growth of northern industrial enterprise in the postbellum years brought with it an accumulation of huge private fortunes. By the turn of the century, persuasive preachers of the "social gospel" urged the wealthy to meet their charitable obligations to society. Andrew Carnegie and John D. Rockefeller , Sr., in the period 1896 to 1918, led the way in creating foundations that could distribute their enormous wealth in what was considered to be the most efficient and socially beneficent manner.
Favorable income tax laws in the 1940s further spurred philanthropic activity. During the early 1950s many American foundations were attacked by right-wing journalists and Congressmen; between 1950 and 1953 the House of Representatives conducted two separate investigations into "subversion and Communist penetration" of the nation's philanthropic foundations. Attacks on the foundations began to subside, however, with the passing of the so-called McCarthy era. Although a number of foundations have been restricted by their charters to specific philanthropic functions, the larger U.S. foundations have devoted themselves to broad areas (see separate articles on Lilly Endowment, Inc .; Ford Foundation ; Rockefeller Foundation ; Sloan Foundation ; and Commonwealth Fund ). The 1980s and 90s saw a doubling in the number of grantmaking foundations, including those developed by financier George Soros and Microsoft founder Bill Gates . Due in part to economic prosperity, foundation giving doubled between 1990 and 1998 to $19.5 billion. In 1997, the largest recipients of grant dollars were education, health, and human services.
See also philanthropy .
Bibliography: See M. Cuninggim, Private Money and Public Service (1972); W. A. Nielsen, The Big Foundations (1972) and The Endangered Sector (1979); D. N. Layton, Philanthropy and Voluntarism: A Bibliography (1987); Foundation Center Staff, Guide to U.S. Foundations, Their Trustees, Officers, and Donors (2 vol., 1999).
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Threonine is catabolized by L-threonine 3-dehydrogenase and threonine dehydratase in hepatocytes from domestic cats (Felis domestica)
Magazine article from: The Journal of Nutrition; 9/1/1996; ; 700+ words
; ...ABSTRACT Isolated hepatocytes were used to study threonine catabolism in kittens, and dietary threonine and crude protein were varied to study enzyme...kittens which had been fed diets containing threonine at 4 or 8 g/kg of diet with either 200...
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Threonine may improve performance of toms fed low-protein diets.
Magazine article from: Feedstuffs; 6/7/1999; ; 700+ words
; ...Minnesota Turkey Growers Assn., examined threonine requirements for market toms. The report...methionine are in "common use" now and threonine is commercially available as well. The...previous studies have indicated that threonine is the third limiting amino acid, after...
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Threonine requirement of neonatal piglets receiving total parenteral nutrition is considerably lower than that of piglets receiving an identical diet intragastrically
Magazine article from: The Journal of Nutrition; 10/1/1998; ; 700+ words
; Threonine Requirement of Neonatal Piglets Receiving...need to be determined. The parenteral threonine requirement was determined in 3-d...examining the effect of varying dietary threonine intakes [0.05-0.6 g/(kg d...
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Threonine Utilization Is High in the Intestine of Piglets1,2
Magazine article from: The Journal of Nutrition; 4/1/2005; ; 700+ words
; ABSTRACT The whole-body threonine requirement in parenterally fed piglets is substantially...nutrition induces intestinal processes in demand of threonine. We hypothesized that the percentage of threonine utilization for oxidation and intestinal protein...
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Threonine Utilization for Synthesis of Acute Phase Proteins, Intestinal Proteins, and Mucins Is Increased during Sepsis in Rats1
Magazine article from: The Journal of Nutrition; 7/1/2007; ; 700+ words
; Abstract We hypothesized that the dietary threonine demand for the anabolic response may be increased...13^C]valine or L-[U-^sup 13^C]threonine, we measured valine and threonine utilization for syntheses of plasma proteins...
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Added threonine may sustain growth in low-protein diets.(Nutrition And Health/Poultry)
Magazine article from: Feedstuffs; 9/1/2003; ; 700+ words
; ...nutritionists the opportunity to utilize L-threonine while maintaining performance with cheaper...functions that have been identified for threonine are those associated with protein synthesis...latter is perhaps where most dietary threonine is targeted because the microcomponents...
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L-threonine use in diets can lower total protein, costs.(Nutrition And Health/Poultry)
Magazine article from: Feedstuffs; 1/5/2004; ; 700+ words
; ...lowered-protein broiler diets with L-threonine resulted in similar performance, body...Financial returns were greater for the L-threonine-supplemented diets. In one of the...Level of poultry meal was fixed, and L-threonine was allowed to least-cost into the...
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Luminal Threonine Concentration Acutely Affects Intestinal Mucosal Protein and Mucin Synthesis in Piglets1-3
Magazine article from: The Journal of Nutrition; 7/1/2008; ; 700+ words
; ...mucin synthesis is sensitive to dietary threonine supply, which suggests that the gut's requirement for threonine may comprise a significant proportion...effects of varying luminal availability of threonine on intestinal protein and mucin syntheses...
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Dietary Threonine Restriction Specifically Reduces Intestinal Mucin Synthesis in Rats
Magazine article from: The Journal of Nutrition; 3/1/2005; ; 700+ words
; ...sensitive than total proteins to dietary threonine intake. For 14 d, male Sprague-Dawley...150% (group 150) of the theoretical threonine requirement for growth. All groups were...indicate that restriction of dietary threonine significantly and specifically impairs...
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Lack of threonine may reduce performance of finishing broilers.
Magazine article from: Feedstuffs; 3/8/1999; ; 700+ words
; Marginal deficiencies of threonine, the third limiting amino acid in...have been done that investigated threonine needs of finishing broilers - and...kcal/kg of diet should receive threonine at 0.68% of the diet, he said...
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threonine
Book article from: The Columbia Encyclopedia, Sixth Edition
threonine , organic compound, one of the 22...mg per lb) of body weight. Although threonine participates in many reactions in bacteria...the catalytic functions of any enzyme. Threonine was isolated from the protein fibrin...
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Post-translational Control
Book article from: Genetics
...usually to the side chain hydroxyl (-OH) of serine, threonine, or tyrosine. This modification results from the action...asparagine or to the hydroxyl of the amino acids serine or threonine. The structure of these carbohydrates can be complex and...
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Glycoprotein
Book article from: Chemistry: Foundations and Applications
...is followed by some other amino acid and then a serine or threonine residue (-Asn-Xaa-Ser/Thr). Carbohydrate is not...of sugar residues to the hydroxyl side chain of serine or threonine residues in polypeptides in the Golgi apparatus. Unlike N...
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Amino Acids
Encyclopedia entry from: Gale Encyclopedia of Alternative Medicine
...acids are tryptophan, lysine, methionine , phenylalaine, threonine, valine, leucine, and isoleucine. The "non –...pains; acts as an antidepressant; and improves memory. Threonine. Makes up a substantial portion of the collagen, elastin...
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Amino Acid Chemistry
Book article from: World of Microbiology and Immunology
...methionine CH3SCH2CH2CH(NH2)COOH, phenylalanine C6H5CH2CH(CH2)COOH, proline C4H8NCOOH, serine HOCH2CH(NH2)COOH, threonine CH3CH(OH)CH(NH2)COOH, cysteine HSCH2CH(NH2)COOH, asparagine, glutamine H2NC(O)(CH2)2CH(NH2)COOH...
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