acromegaly
From: The Columbia Encyclopedia, Sixth Edition
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Date: 2008
acromegaly , adult endocrine disorder resulting from hypersecretion of growth hormone produced by the pituitary gland. Since the bones cannot increase in length after full growth is attained, there is a disproportionate thickening of bones, predominantly in the skull and small bones of the hands and feet. Fingers and toes become broadened and spadelike, the skull increases in size, and the cheek bones and jaws protrude. Many of the soft tissues, such as the tongue and liver, enlarge. Frequently glucose metabolism is disturbed, leading to diabetes mellitus. Acromegaly is usually caused by a tumor of the pituitary; treatment consists of irradiation or surgical removal of the tumor. Onset of the disease can also occur in children, before the epiphyses of the bones are closed. In such cases the disorder leads to gigantism .
Author not available, ACROMEGALY.,
The Columbia Encyclopedia, Sixth Edition 2008
The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press
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Effect of Sex and Assay Method on Serum Concentrations of Growth Hormone in Patients with Acromegaly and in Healthy Controls
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Background: Diagnosis and follow-up of acromegaly is based on measurements of serum growth ... median age, 55.2 years) and 7 untreated acromegaly patients (4 women and 3 men; median ... growth hormone (GH)5 as the cause of acromegaly is confirmed by measuring serum GH during ...
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A case of acromegaly in pregnancy: Concomitant transsphenoidal adenomectomy and cesarean section
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Long-Term Survival Benefits of Early Diagnosis, Treatment of Acromegaly.
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... quickest, most effective route to curing acromegaly but a number of medical approaches are ... importance of recognizing and treating acromegaly early since the physical toll of the ... is from two to five times higher in acromegaly patients due to significantly elevated ...
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Octreotide treatment of acromegaly during pregnancy
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To the Editor: When symptomatic acromegaly occurs during pregnancy, the treatment ... somatostatin analogue drug approved to treat acromegaly) during pregnancy. This issue is addressed ... following patient. A 29-year-old woman with acromegaly underwent transsphenoidal resection ...
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Diagnosis and Treatment of Acromegaly.(Statistical Data Included)
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... population of 1 million, 60 to 70 adults have acromegaly, and about three new cases are detected ... important because of the association between acromegaly and diabetes and cardiovascular, cerebrovascular ... excessive growth hormone can lead to acromegaly. The characteristic changes in appearance ...
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Lanreotide approved for long-term acromegaly treatment.(Metabolic Disorders)
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&type=1 "The Independent (London, England)")
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Health: My hands and feet started growing... Julie Tierney only discovered she had acromegaly, a form of gigantism, when her shoes and rings no longer fitted. But a new drug offers hope, reports Kate Hilpern.(Features)
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... 000 people in the UK suffering from acromegaly. The name comes from the Greek words ... Julie knows all too well, patients with acromegaly can also suffer from excessive sweating ... odour, as well as fatigue and weakness. Acromegaly is a disorder that is caused when the ...
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FDA approvals.(pegvisomant (Somavert) for acromegaly treatment; enfuvirtide (Fuzeon) for HIV treatment)
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... unusual presentation of acne conglobata associated with acromegaly. Case Report A 55 year-old male presented with multiple ... diarrhea and uveitis. Physical examination revealed acromegaly with frontal bossing, prognathism, a barrel chest ... Axillae and groins were spared. A clinical diagnosis of ...
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Independent Pursuits: Words - acromegaly, n
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... edition of The New York Times but Bernard Levin's medical metaphor was to calculate its weight and size as an "experiment in acromegaly". Rarely used other than technically, it is a late-19th-century coining for the doubly gigantic, for it comprises the Greek ...
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n Acromegaly drug endorsed
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... internal organs after approving a drug developed by the pharmaceutical company Ipsen. Somatuline has been approved to treat acromegaly. Patients with the condition, including the actor Carel Struycken (above), who played Lurch in the Addams Family movies, generally ...
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Diagnosis and treatment of acromegaly.
American Family Physician; 7/1/1995; Maugans, Todd A. Coates, Michael L.; 3136 words;
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