mutagen
From: The Columbia Encyclopedia, Sixth Edition
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Date: 2008
mutagen see mutation .
Author not available, MUTAGEN.,
The Columbia Encyclopedia, Sixth Edition 2008
The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press
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Sorting out cancer IQs in browned meat. (food-borne mutagens)
Science News; 1/8/1994; Raloff, J.; 557 words;
... meats also produces a host of powerful mutagens know as heterocyclic amines (HCAs). In ... researchers have linked these food-borne mutagens -- especially one known as IQ -- to an ... identified during the 1980s as a direct-acting mutagen in the Ames test, a bacterial assay used ...
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More bad news about that tasty browning. (browning food can create mutagens)
Science News; 7/11/1987; 176 words;
More bad news about that tasty browning The Maillard reaction--a heat-activat ... Italy report that Maillard reactions in meat also produce mutagens, substances that cause genetic mutations. Because ribose ... JOURNAL OF FOOD SCIENCE, they report that this sugar forms mutagenic products with most of the amino ...
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Mutagens in air: they may be a gas. (interaction of chemical pollutants in presence of sunlight)
Science News; 3/16/1985; Raloff, Janet; 588 words;
... converted photochemically into gas-phase mutagens. Paul B. Shepson of Northrop Services ... justified, he says. Though we know PAHs are mutagenic, no one has really addressed the question ... hydrocarbons contribute to the overall mutagenic activity of urban air. The Ames test ...
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Food mutagens
The Journal of Nutrition; 3/1/2003; Goldman, Radoslav; Shields, Peter G; 11214 words;
... animal models indicate that aflatoxins are mutagenic and carcinogenic (46). Epidemiological studies ... to address many questions regarding food mutagens. These studies are being performed in the ... most direct evidence for the role of food mutagens in carcinogenesis. However, this is problematic ... focused ...
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Nisshin Food Products Upgrades Its Mutagen Testing Method
JCNN News Summaries - Japan Corporate News Network; 3/30/2006; Aki Tsukioka; 96 words;
... Food Products has updated its current mutagen testing method NESMAGET (Nisshin's Evaluation ... cells to NESMAGET in order to identify mutagens in food with a higher accuracy. In fact ... first screening of identifying human mutagens derived from drugs and foods. Details ...
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DNA damage induced by mutagens in plant and human cell nuclei in acellular comet assay
Folia Histochemica et Cytobiologica; 1/1/2006; Juchimiuk, Jolanta; Gnys, Agnieszka; Maluszynska, Jolanta; 3880 words;
... human cells to physical and chemical mutagens showed differences in their sensitivity ... DNA-damaging effects of two chemical mutagens: maleic acid hydrazide (MH) and N-methyl ... compared to the nuclei of plant cells to mutagenic treatment with the applied doses of MH ...
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Carcinogens and mutagens. (food compositions) (Coffee Break with Dr. Samuel Lee) (Column)
Tea & Coffee Trade Journal; 1/1/1993; Lee, Samuel; 941 words;
... contain carcinogenic (cancer causing) or mutagenic (causing mutations in animals) elements ... carbohydrate, when caramelized, produces mutagens and other harmful chemicals. This was ... flied potatoes as well as coffee contain mutagens in addition to the carcinogen but in ...
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Development of Large-scale Medicago truncatula Tagged Mutants Using Tnt1 Retrotransposon as a Mutagen
In Vitro Cellular & Developmental Biology; 4/1/2004; Tadege, Million; Kwak, Younsig; Ratet, Pascal; Mysore, Kirankumar; 317 words;
... activated to transpose in tissue culture, but with insertions stable in progenies. We are employing this property of Tnt1 to mutagenize and tag the whole genome of the model legume Medicago truncatula. Tnt1 was first introduced into M. truncatula (R108) by Agrobacterium ...
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NO HAZARD?
The Patriot Ledger Quincy, MA; 2/13/2002; Sue Reinert; 705 words;
... Harvard School of Public Health study on Mutagen X in public drinking water did not find ... has a long chemical name but is known as Mutagen X, or MX, was found by researchers from ... it. It's really not a health hazard." Mutagens are substances that damage genes and Mutagen ...
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Propylene Oxide: Genotoxicity Profile of a Rodent Nasal Carcinogen
Critical Reviews in Toxicology; 7/1/2007; Albertini, Richard J; Sweeney, Lisa M; 25897 words;
... human diploid fibroblasts. Environ. MoI. Mutagen. 32:223-228. Ciliberti, A., Maltoni, C ... mutagenicity of ethylene oxide. Environ. MoI. Mutagen. 16:85-103. Djuric, Z., Hooberman, B.H ... and Sinsheimer, J.E. (1986). Reactivity of mutagenic propylene oxides with deoxynucleosides and DNA. Environ ... .
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Inferring Somatic Mutation Rates Using the Stop-Enhanced Green Fluorescent Protein Mouse
Genetics; 9/1/2007; Ro, Simon; Rannala, Bruce; 5523 words;
... mutations. Mice treated with a potent mutagen, N-ethyl-N-nitrosourea (ENU), and mice ... interval for the relative effect of the mutagen (the ratio of the rate of mutation during the interval of mutagen exposure to the rate of background mutation ...
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Generating Novel Allelic Variation Through Activator Insertional Mutagenesis in Maize
Genetics; 3/1/2007; Bai, Ling; Singh, Manjit; Pitt, Lauren; Sweeney, Meredith; Brutnell, Thomas P; 7934 words;
... Activator (Ac) has been exploited as an insertional mutagen to disrupt, clone, and characterize genes in a number ... Ac) and Dissociation (Ds) are powerful insertional mutagens in plants and have been used to isolate genes (KUNZE ... general feature of Ac/Ds has been exploited in maize to mutagenize genes ...
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The CYP1A1 Genotype May Alter the Association of Meat Consumption Patterns and Preparation with the Risk of Colorectal Cancer in Men and Women1
The Journal of Nutrition; 2/1/2005; Murtaugh, Maureen A; Sweeney, Carol; Ma, Khe-ni; Caan, Bette J; Slattery, Martha L; 6360 words;
... even with high exposure to dietary sources of mutagens. CYP1A1 plays a role in activation of PAHs ... the CYP1A1 wild type and a high white meat mutagen index instead of with the variant genotype ... alone, GSTM1 polymorphisms alone, or red meat mutagen alone with colon (15)and rectal cancer (16 ... the GSTM1 ...
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CHEMICAL MUTAGENESIS-A PROMISING TECHNIQUE TO INCREASE METAL CONCENTRATION AND EXTRACTION IN SUNFLOWERS
International Journal of Phytoremediation; 3/1/2007; Nehnevajova, Erika; Herzig, Rolf; Federer, Guido; Erismann, Karl-Hans; Schwitzguébel, Jean-Paul; 6552 words;
... lines-were treated with the chemical mutagen ethyl methanesulfonate (EMS). The effect ... Ahloowalia, and Sigubjornsson, 1995). The mutagenic treatment has also been successful to ... sunflower seeds were exposed to the chemical mutagen ethyl methanesulfonate (EMS). Optimization ...
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The Ames Salmonella/microsome mutagenicity assay: issues of inference and validation.
Journal of the American Statistical Association; 9/1/1989; Margolin, Barry H. Kim, Byung Soo Risko, Kenneth J.; 7758 words;
... part of the chemical registration process. A mutagen is an agent, such as X rays or a chemical, that ... carcinogens is clear; the parallel concern for mutagens may not be. First, mutagens may exert their effects on germ cells, thereby ...
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Nisshin Food Products Upgrades Its Mutagen Testing Method.
JCNN News Summaries; 3/30/2006; 108 words;
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Change of venue: taking environmental mutagen research to the developing world.(NIEHS News)
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Cooking meat adds to cancer-causing mutagens.
Nutrition Health Review; 9/22/1989; 177 words;
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The Biological Basis of Hutchinson-Gilford Syndrome (HGS): Relationship to Mutagens in the Lamin A/C Gene (LMNA) and to Other Known Laminopathies. (Fellowships, Grants, & Awards).
Environmental Health Perspectives; 5/15/2003; 567 words;
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3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) and mutagenic activity in Massachusetts drinking water. (Articles).
Environmental Health Perspectives; 2/1/2002; Wright, J. Michael Schwartz, Joel Vartiainen, Terttu Maki-Paakkanen, Jorma Altshul, Larisa Harrington, Joseph J. Dockery, Douglas W.; 7848 words;
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Mechanisms of the genotoxicity of crocidolite asbestos in mammalian cells: implication from mutation patterns induced by reactive oxygen species. (Articles).
Environmental Health Perspectives; 10/1/2002; Xu, An Zhou, Hongning Yu, Dennis Zengliang Hei, Tom K.; 6692 words;
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A study on the mutagenicity of tobacco smoke from low-tar cigarettes.
Archives of Environmental Health; 7/1/1990; Chortyk, Orestes T. Chamberlain, William J.; 4537 words;
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Estimating the extent of the health hazard posed by high-production volume chemicals. (Articles).
Environmental Health Perspectives; 9/1/2001; Cunningham, Albert R. Rosenkranz, Herbert S.; 5502 words;
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Of mice and molecules: research with genetically modified mouse models.(Essay on: Genetically Modified Mouse Models)
Environmental Health Perspectives; 8/15/2005; Shostak, Sara; 6818 words;
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Assessment of 1,3-butadiene exposure in polymer production workers using HPRT mutations in lymphocytes as a biomarker. (Articles).
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