Jean-Marie Lehn
The Columbia Encyclopedia, Sixth Edition
Jean-Marie Lehn , 1939-, French chemist, Ph.D. Univ. of Strasbourg, 1963. A professor at Louis Pasteur Univ. (1970-78) and the Collège de France (1979-), Lehn did ground-breaking research in the creation of artificial enzymes. Expanding on the work of Charles J. Pedersen , Lehn synthesized a three-dimensional molecule that combined with a neurotransmitter in the brain, opening the possibility of creating artificial enzymes that function better than natural enzymes. He shared the 1987 Nobel Prize in Chemistry with Pedersen and Donald J. Cram for the development and application of molecules with highly selective, structure specific interactions, i.e., molecules that can "recognize" each other and choose which other molecules they will form complexes with.
Author not available, LEHN, JEAN-MARIE.,
The Columbia Encyclopedia, Sixth Edition 2008
Find more facts and information related to the .
The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press
Related newspaper, magazine, and trade journal articles from HighBeam Research
(Including press releases, facts, information, and biographies)
|
Cages, cavities and clefts: by building and setting molecular traps, chemists shed light on how one molecule recognizes another.
; ...creating and manipulating simple artificial enzymes, chemists can test their theories...enzymes.' It's even possible to prepare artificial enzymes capable of catalyzing reactions for...attractive in the first constructions of artificial enzymes.' Although this choice limited the...
Read more
|
|
CHEM-BIO-TECH 2007.(Where 2B & Y: Announcements of conferences, symposia, workshops, meetings, and other upcoming activities)(Calendar)
; ...biosynthesis, biocatalysis, and organic synthesis through artificial enzymes and other emerging biotechnological applications. Attention...and Bio-Inorganic Chemistry, Biosynthesis, Biocatalysis, Artificial Enzymes 4. Analytical Methods Applied to Molecular Recognition...
Read more
|
|
Artificial Enzymes that Outdo Mother Nature?
; ...enzymes with these metals in their active site are not found in nature. Akira Harada, who developed the catalyst, says that artificial enzymes based on these metals could potentially revolutionize catalysis. The researchers created the catalyst by treating immune...
Read more
|
|
Enzyme Seeker.(Brief Article)
; ...more effective than enzymes currently used, the researchers say. FRET uses a substrate composed of positively charged artificial enzymes that contain a fluorescent molecule. When active enzymes come into contact with the substrate they adhere to it and fluoresce...
Read more
|
|
Clean label ingredients with simple declarations.(ingredients)(Brief Article)
; Ulrick & Short have created a successful range of starches flours and proteins, produced without the use of chemicals, artificial enzymes or genetic modification. The company's ingredients are also free from e-numbers, preservatives and added colouring. Their...
Read more
|
|
(book reviews)
; ...Imagine a world in which we had the same control over atoms and molecules that Nature does. It would be possible to make artificial enzymes to catalyse the synthesis of any molecule. Electronic components based on single molecules could be incorporated into...
Read more
|
|
Artificial enzymes.(industry PATENTS)(Brief article)
; U.S. Patent 7,232,861 (June 19, 2007), Enzyme-Mimicking Polymers, Koji Sode (Meguro-ku, Tokyo, Japan). Enzymes are the catalysts of life, integral to more reactions than we can count. An enzyme is a large polymer that first grabs a reactant, puts it in contact with a reactive functional group, and
Read more
|
|
Welcome message.(from the Vancouver CSC 2002 Conference Chair)(Brief Article)
; ...the design, synthesis and study of molecules that imitate enzymatic reactions, work that has included the development of artificial enzymes. We are very pleased to have Professor Breslow as our Opening Plenary Lecturer. The meeting will be held on the beautiful...
Read more
|
|
Large Artificial Antibodies Capable of Dissolving in Water.(Brief Article)
; ...molecules such as cholesterol and comycin. This work will be of interest to pharmaceutical firms, for unlike previous artificial enzymes which can only dissolve in organic solvents, the cyclodextrin version can be mixed in water, making it a candidate for...
Read more
|
|
Technical program.(plenary lecture from Professor Ronald Breslow)(Brief Article)
; ...enzymatic reactions. This work has included the development of remote functionalization reactions and the development of artificial enzymes. Recently he has developed a new group of cytodifferentiating agents with potential use in cancer chemotherapy. He is...
Read more
|
For more facts and information,
see all related premium articles
Related entries from encyclopedias, dictionaries, and thesauruses
|
Donald James Cram
...synthesizing three-dimensional molecules that could mimic the functioning of natural molecules. With Pedersen and Jean-Marie Lehn , Cram was awarded the 1987 Nobel Prize in Chemistry for the development and application of molecules with highly...
Read more
|
|
Charles John Pedersen
...the 1960s, he did groundbreaking work in the creation of artificial compounds. His work was later expanded upon by Jean-Marie Lehn and Donald Cram , who synthesized enzymes. For their syntheses of molecules that mimic important biological processes...
Read more
|