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Nucleotide excision repair (NER) of carcinogen adducts

This cartoon animation shows how DNA damage is fixed by a process called "nucleotide excision repair" (NER). The target is the DNA adducted by the human bladder carcinogen 4-aminobihpheny. The NER machinery represented by cartoon mice takes the problematic portion of the DNA and trash it. The missing strand is replaced by a new DNA strand. Prepared by Josh Vallee (pharmacy student, 2007) Bongsup Cho (professor)

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