What's The Difference Between Mitosis and Meiosis?
A scientific spoof on the classic by Dr. Dre and Xzibit.
What's the difference between mitosis and meiosis?
What's the difference between mitosis and meiosis?
Lets explain each, first we got mitosis
The cell starts off in interphase, where it's kickin' with the homies
The cell grows and grows, till its ready to split from them hoes
With all its new chromosomes, its ready to goes
Next is prophase, the chromatids pair at the centromere
The mitotic spindle forms outside the nuclear envelope here.
The centrosomes move to opposite poles. That's where they stays.
The chromosomes on the plate we call it metaphase (yeah).
Comin is Anaphase, microtubules pull back at the kinetochore
Separate the chromosomes; make 'em look like they're tore.
Last is telophase, the new nucleolus and envelope formed
With the help of cytokinesis, two daughter cells are borned.
Break at the cleavage furrow, the cell's pinched in two
If ya didn't know it before, we aim to give ya a clue.
What's the difference between mitosis and meiosis?
Meiosis does the gametes, while somatics from mitosis
Meiosis I has the unique chromosome pairing of a tetrad
Crossing over at chiasmata, that's synapsis, its really rad.
Meiosis is next, looks a lot like the first one
If it didn't have two phases, it might be mitosis' son.
Starts off the same, interphase begins
Chromosomes duplicate, rollin in the nuclear envelope like rims
Now hear it gets different, we hit prophase uno
Homologous chromosomes pair, makin a tetrad sumo
Because synapsis pairs the chromosomes, crossing over occurs
At the chiasmata, which holds until anaphase, yessir!
We hit up metaphase, it's the same as before
Tetrads line up, microtubules attached to the kinetochores
Anaphase I, the paired homologues shoot to their pole
Centrosomes pull sister chromatids apart, cell becomin' oval
Meiosis I ends with telophase I, wit some cytokinesis
These chromosomes are still in a pair, like Reese's pieces
Two haploid cells are formed, the furrow separates them again
With Meiosis I done, we can start all where we begin.
Meiosis II and mitosis, they are almost the same
Except one makes 2 diploids, while 4 haploids is what II (what II) claims.
[Chorus]