MHC class II - bacterial toxin - TCR

The bacterial peptide (toxic to our gut) which is bound in the MHC-II molecule's groove was shown structurally to interact with a surface peptide (TCR) of our T cell. Reference for more info Fernandez, MM., Guan, R., Swaminathan, CP., Malchiodi, EL., Mariuzza, RA. (2006) J.Biol.Chem. 281: 25356-25364 Rasmol Roger Sayle & E. James Milner-White. Trends in Biochemical Sciences, 1995,20(9):374. Herbert J. Bernstein, Trends in Biochemical Sciences,2000,25(9):453-455.

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MHC class II - bacterial toxin - TCR

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