tamoxifen

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A Dictionary of Nursing

The Columbia Encyclopedia, Sixth Edition

tamoxifen

tamoxifen , synthetic hormone used in the treatment of breast cancer . Introduced in 1978, tamoxifen is used to prevent recurrences of cancer in women who have already undergone surgery to remove their tumors. In 1998, a large study of healthy women at high risk for breast cancer showed that tamoxifen can also prevent first occurrence of the disease: women who took the drug had a 45% lower incidence of cancer that those who received a placebo. However, adverse effects (including uterine cancer) and other concerns await further study.

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tamoxifen

A Dictionary of Nursing | 2008 | Â© A Dictionary of Nursing 2008, originally published by Oxford University Press 2008. (Hide copyright information) Copyright

tamoxifen (tam-oks-i-fen) n. a drug administered orally in the treatment of breast cancer: it binds with hormone receptors in the tumour to inhibit the effect of oestrogens (see anti-oestrogen, selective (o)estrogen receptor modulator). It is also used to induce ovulation in the treatment of female infertility. Trade name: Nolvadex D.

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"tamoxifen." A Dictionary of Nursing. Oxford University Press. 2008. Encyclopedia.com. 5 Jul. 2009 <http://www.encyclopedia.com>.

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Free newspaper and magazine articles

	Is Tamoxifen Safe and Effective?(for breast cancer treatment and prevention) Newspaper article from: Women's Health Letter; 4/1/2001
	The Breast Cancer Prevention Trial: new finding on tamoxifen. Newspaper article from: HealthFacts; 4/1/1994
	The Small Blue Cell Dilemma Associated With Tamoxifen Therapy.(Statistical Data Included) Magazine article from: Archives of Pathology & Laboratory Medicine; 8/1/2001

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	Is Tamoxifen Safe and Effective?(for breast cancer treatment and prevention) Newspaper article from: Women's Health Letter; 4/1/2001; ; 700+ words ; Tamoxifen, otherwise known as Nolvadex, is a drug used both to...controversy surrounding the safety and effectiveness of tamoxifen. The more you understand about it, the easier it will be for you to make wise health-care choices. Simply put, tamoxifen prevents estrogen-receptor positive (ER-positive) ... Read more
	The Breast Cancer Prevention Trial: new finding on tamoxifen. Newspaper article from: HealthFacts; 4/1/1994; 700+ words ; Tamoxifen, the antiestrogen drug now under investigation as a breast...cancer patients, half of whom have been treated with tamoxifen. It resurrects an old controversy over the wisdom of...the 16,000 participants, aged 35 or older, are taking tamoxifen, and half are taking a placebo. Earlier research ... Read more
	The Small Blue Cell Dilemma Associated With Tamoxifen Therapy.(Statistical Data Included) Magazine article from: Archives of Pathology & Laboratory Medicine; 8/1/2001; ; 700+ words ; Tamoxifen is a nonsteroidal antiestrogenic medication that has...estrogen by binding to cytoplasmic estrogen receptors, tamoxifen also has an estrogen-agonist effect on the female genital...endometrial polyps, have been found to be associated with tamoxifen administration.[2] Increased maturation of vaginal ... Read more
	Tamoxifen as a breast cancer preventive - many questions remain. Newspaper article from: HealthFacts; 5/1/1998; ; 700+ words ; ...headlines across the country last month. Tamoxifen, a drug prescribed for over two decades...breast cancer among the women taking tamoxifen as compared with those taking an inactive...regarding the drug's risks. The women taking tamoxifen had more than twice the rate of endometrial... Read more
	Breast cancer drug to be approved for the healthy but high risk. (tamoxifen) Newspaper article from: HealthFacts; 10/1/1998; 700+ words ; ...recommend approval of the breast cancer drug, tamoxifen, for the short-term reduction in the...may be lost once the prescription of tamoxifen to healthy women becomes widespread...trial results which merely indicate that tamoxifen can reduce the incidence of breast cancer... Read more
	Tamoxifen shown to reduce risk of ER-positive breast cancer.(JUST IN)(estrogen receptor) Magazine article from: ONS Connect; 6/1/2007; ; 431 words ; Two studies have suggested that tamoxifen reduces the long-term risk of breast cancer. Tamoxifen is an oral selective estrogen receptor modulator...IBIS). Women took either a daily dose of tamoxifen or a placebo for five years. Eight years... Read more
	Tamoxifen for "Prevention:" New Risk/Benefit Analysis. Newspaper article from: HealthFacts; 1/1/2000; ; 534 words ; ...women and doctors decide who should use tamoxifen therapy, a new risk/benefit analysis...800 participants who had been taking tamoxifen showed a 49% lower rate of breast cancer...questions that remains is this: Does tamoxifen actually prevent breast cancer or merely... Read more
	Tamoxifen: a drug to prevent breast cancer found to cause adverse eye effects. Newspaper article from: HealthFacts; 7/1/1992; 524 words ; ...healthy women are being recruited to take tamoxifen in the Breast Cancer Prevention Trial...for growth. Compared with Chemotherapy, tamoxifen (brand name: Nolvadex) has relatively...a study of 63 people (one man) taking tamoxifen following initial treatment for breast... Read more
	Study Tries Breast Cancer Drug Tamoxifen for Abortion Yet Another Chemical Abortifacient? Magazine article from: National Right to Life News; 3/15/1999; ; 700+ words ; ...chemical abortion method that employs tamoxifen, a powerful anti-estrogenic compound...examined the effects of a regimen of tamoxifen used alone or in combination with misoprostol...after completing the four-day dose of tamoxifen (20mg once a day for four days). Another... Read more
	Sequential therapy with tamoxifen and aromatase inhibitors in early-stage postmenopausal breast cancer: a review of the evidence. Magazine article from: Oncology Nursing Forum; 7/1/2008; ; 700+ words ; ...recurrent or contralateral breast cancer. Tamoxifen has been the mainstay of adjuvant endocrine...two or three years of treatment with tamoxifen. The implications for nursing practice also are discussed. Tamoxifen: Benefits and Limitations Approximately... Read more