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Ribosomes Reveal Their RNA Secrets.(Brief Article)
Science News; 8/12/2000; Gorman, J.; 537 words
; Ribosomes, the cell's protein factories, have been ... atomic scale, scientists know what most of the ribosome looks like. A new map reveals most of the ... larger of the two subunits of a bacterial ribosome. The map suggests where and how the ribosome chemically stitches amino acids into a protein. The ...
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Exploring the Flexibility of Ribosome Recycling Factor Using Molecular Dynamics
Biophysical Journal; 10/1/2005; Stagg, Scott M; Harvey, Stephen C; 787 words
; ABSTRACT Ribosome recycling factor is proposed to be flexible ... cryoelectron microscopic structure of the RRF/ribosome complex, and in the crystal structure ... in prokaryotes. the complex of the 70S ribosome, deacylated tRNA, and mRNA (the post ...
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Genetic and Biochemical Interactions Among Yar1, Ltv1 and RpS3 Define Novel Links Between Environmental Stress and Ribosome Biogenesis in Saccharomyces cerevisiae
Genetics; 12/1/2004; Loar, Jesse W; Seiser, Robert M; Sundberg, Alexandra E; Sagerson, Holly J; Et al; 787 words
; ABSTRACT In the yeast S. cerevisiae, ribosome assembly is linked to environmental conditions ... transcriptional regulation of genes required for ribosome biogenesis. In this study we show that ... suppresses both the stress sensitivity and the ribosome biogenesis defect of Δyar1 mutants ...
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The Weird and Wonderful World of Bacterial Ribosome Regulation
Critical Reviews in Biochemistry and Molecular Biology; 5/1/2007; Wilson, Daniel N; Nierhaus, Knud H; 787 words
; ... functional proteins is performed on the ribosome. In Escherichia coli up to 40% of the ... energy turnover is channelled toward the ribosome and protein synthesis. Thus, elaborate ... characterized factors that regulate the ribosome, ranging from processing, modification ...
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Piecing together the ribosome; for some, it's a lifelong puzzle. (scientists Richard Brimacombe and Harry F. Noller construct models of ribosomes) (Cover Story)
Science News; 11/5/1994; Pennisi, Elizabeth; 787 words
; ... biologists with his computer rendition of the ribosome, the cell's protein-producing machine ... works on solving the structure of the ribosome. I need a problem that's like a crossword ... where he thinks the various atoms in the ribosome's core are located. No sooner have they ...
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Isolation and Characterization of an RIP (Ribosome-Inactivating Protein)-Like Protein from Tobacco with Dual Enzymatic Activity1[w]
Plant Physiology; 1/1/2004; Sharma, Neelam; Park, Sang-Wook; Vepachedu, Ramarao; Barbieri, Luigi; Et al; 787 words
; Ribosome-inactivating proteins (RIPs) are N-glycosidases that ... gel filtration chromatography in combination with yeast ribosome depurination assays. TRIP has a molecular mass of 26 ... adenine residues from ribosomal (Artemia sp. and rat ribosomes) and non-ribosomal substrates (herring sperm DNA, rRNA ...
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From Ribosome to Riboswitch: Control of Gene Expression in Bacteria by RNA Structural Rearrangements
Critical Reviews in Biochemistry and Molecular Biology; 11/1/2006; Grundy, Frank J; Henkin, Tina M; 787 words
; ... translation initiation complex to the ribosome binding site, thereby preventing protein ... coding region, and the processivity of the ribosome during translation of the leader peptide ... switch that regulates accessibility of the ribosome binding site of the downstream gene ...
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WHAT'S IN A RIBOSOME?
The Boston Globe; 8/29/2000; STEPHEN REUCROFT AND JOHN SWAIN; 112 words
; Scientists finally are getting a good look at the structure of ribosomes, the tiny factories that cells use to turn genetic information ... two RNA molecules and 31 proteins that make up a bacterial ribosome. The shape is complex and somewhat unexpected, with RNA at ...
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Fine-Tuning of Translation Termination Efficiency in Saccharomyces cerevisiae Involves Two Factors in Close Proximity to the Exit Tunnel of the Ribosome
Genetics; 11/1/2007; Hatin, Isabelle; Fabret, Céline; Namy, Olivier; Decatur, Wayne A; Rousset, Jean-Pierre; 787 words
; ... factors close to the exit tunnel of the ribosome, directed the strongest antisuppression ... newly synthesized polypeptide from the ribosome before recycling the translational machinery ... for the release of polypeptide from the ribosome (Takanami and Yan 1965). The misincorporation ...
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Crosslinking of Ribosomal Proteins to RNA in Maize Ribosomes by UV-B and Its Effects on Translation1[w]
Plant Physiology; 10/1/2004; Casati, Paula; Walbot, Virginia; 787 words
; ... mays) leaves, UV-B radiation damages ribosomes by crosslinking cytosolic ribosomal proteins ... exposure. After 16 h without UV-B, damaged ribosomes were eliminated and translation was restored ... translation of some ribosomal proteins after ribosome damage in mammalian fibroblast cells ...
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