quinidine

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quinidine

The Columbia Encyclopedia, Sixth Edition | 2008 | The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press. (Hide copyright information) Copyright

quinidine , heart muscle relaxant used to maintain regular heart rhythm patterns. It is an alkaloid chemically similar to quinine and, like quinine, occurs naturally in some species of cinchona trees. Quinidine slows the rate of blood flow in heart chambers and lowers the excitability of the muscle. Quinidine is a general relaxant of smooth muscle and acts as a dilator of larger blood vessels. It has also been used to reduce fever and to treat malaria. Synchronized electric shock has largely replaced quinidine as a method of establishing more normal heart rhythms.

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quinidine

A Dictionary of Nursing | 2008 | © A Dictionary of Nursing 2008, originally published by Oxford University Press 2008. (Hide copyright information) Copyright

quinidine (kwin-i-deen) n. a drug that slows down the activity of the heart and is administered by mouth to control abnormal and increased heart rhythm. Trade name: Kinidin Durules.

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Availability and Use of Parenteral Quinidine Gluconate for Severe or Complicated Malaria.(recommendation for hospitals to improve their stocking of quinidine gluconate)(quinidine gluconate)(Brief Article)
Newspaper article from: Morbidity and Mortality Weekly Report; 12/22/2000; 700+ words ; Since 1991, quinidine gluconate, a class la anti-arrhythmic...availability of and delays in obtaining quinidine gluconate have contributed to adverse...newer anti-arrhythmics have replaced quinidine for many cardiac indications, some...
Elimination of late potentials by quinidine in a patient with Brugada syndrome
Magazine article from: Journal of Electrocardiology; 1/1/2006; ; 700+ words ; Abstract The beneficial effects of quinidine on ST-segment elevation, inducible...This is the first report describing quinidine-induced elimination of the late potential...reserved. Keywords: Brugada syndrome; Quinidine; Late potential; Signal-averaged...
Quinidine for cardioversion of AF.
Magazine article from: Clinical Advisor; 12/1/2005; 700+ words ; ...note that a combination of digoxin and quinidine sulfate will convert most patients without...every day thereafter. On day two, I add quinidine sulfate 200 mg four times daily. If...the fourth or fifth day, I push the quinidine to 400 mg four times daily. If nothing...
Treatment of severe plasmodium falciparum malaria with quinidine gluconate: discontinuation of parenteral quinine from CDC service. (Center for Disease Control)
Newspaper article from: Morbidity and Mortality Weekly Report; 4/12/1991; 700+ words ; ...falciparum infections is parenteral quinidine gluconate. Therefore, effective immediately...States (1), continuous infusion of quinidine gluconate is recommended. A loading dose of 10 mg of quinidine gluconate (equivalent to 6.2 mg quinidine...
Availability of parenteral quinidine gluconate for treatment of severe or complicated malaria. (delay in getting quinidine gluconate to treat two malaria patients is believed to have been a factor in their deaths)(Brief Article)
Newspaper article from: Morbidity and Mortality Weekly Report; 6/14/1996; 676 words ; ...States in which a delay in obtaining quinidine gluconate for intravenous therapy was...the patients' deaths. Since 1991, quinidine gluconate, a well-known and widely...strains of P. falciparum. intravenous quinidine is indicated whenever oral therapy is...
Influence of quinidine, fluvoxamine, and ketoconazole on the enantioselective pharmacokinetics of citalopram in rats.(Clinical report)
Magazine article from: Canadian Journal of Physiology and Pharmacology; 11/1/2008; ; 700+ words ; ...vitro and in vivo studies indicate that quinidine inhibits CYP2D. Law et al. (2000) reported that quinidine administered to rats at the dose of 80...metabolism of CITA enantiomers associated with quinidine, fluvoxamine or ketoconazole in rats...
Massachusetts Inventors Develop Quinidine-Based Catalyst
News Wire article from: US Fed News Service, Including US State News; 12/29/2007; 540 words ; ...have developed a quinine-based or quinidine-based catalyst. An abstract of the...invention relates to quinine-based and quinidine-based catalysts. Another aspect of...preparing a derivatized quinine-based or quinidine-based catalyst comprising reacting...
Quinidine/Verapamil Excel in Recurrent Atrial Fib. (Better Than Sotalol After Cardioversion).(fibrillation )
Magazine article from: Internal Medicine News; 11/15/2001; ; 700+ words ; STOCKHOLM -- Quinidine plus verapamil was better than sotalol...patients, a daily dosage of 480 mg of quinidine plus 240 mg of verapamil was given...on sotalol, and 70% for those on quinidine plus verapamil. Both treatment arms...
Quinidine effective in treatment of electrical storm.
Newspaper article from: Obesity, Fitness & Wellness Week; 8/21/2004; 573 words ; ...NewsRx.com & NewsRx.net) -- Quinidine can be effective in treatment of electrical...cardioverter defibrillator." "Oral quinidine bisulphate at a dose of 1000 mg/day...stimulation." "This case suggests that quinidine, by virtue of its blocking action on...
Heart rhythm drugs worse than no treatment. (quinidine)
Newspaper article from: HealthFacts; 2/1/1992; ; 700+ words ; People treated with quinidine for abnormal heart rhythms (arrhythmias...November 1991). It also discovered that quinidine, although widely used for over half...have come to rely more heavily on quinidine, whose benefits they believe outweigh...

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