properdin

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properdin

The Columbia Encyclopedia, Sixth Edition | 2008 | The Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press. (Hide copyright information) Copyright

properdin , protein found in the blood serum of humans and some of the higher animals that appears to participate in certain specific immune responses. It is associated with the engulfing of foreign particles and invading cells by phagocytes and with tissue inflammation (see blood ; immunity ). Properdin has been isolated in highly purified form.

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properdin

A Dictionary of Nursing | 2008 | © A Dictionary of Nursing 2008, originally published by Oxford University Press 2008. (Hide copyright information) Copyright

properdin (proh-per-din) n. a group of substances in blood plasma that, in combination with complement and magnesium ions, is capable of destroying certain bacteria and viruses.

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Related articles from newspapers, magazines, and more

Gliatech Receives Allowance of U.S. Patent Claims for Anti-Properdin Technology.
PR Newswire; 10/3/2001; 700+ words ; ...patent claims covering the use of anti-properdin agents as treatments to inhibit harmful...developing therapeutic antibodies to properdin as potential treatments for acute inflammatory...our intellectual property around anti-properdin agents and their promising utility as...
Gliatech receives allowance of United States patent claiming therapeutic antibodies to properdin.(Brief Article)
Newspaper article from: BIOTECH Patent News; 10/1/2001; 700+ words ; ...patent claims covering the use of anti-properdin agents as treatments to inhibit harmful...developing therapeutic antibodies to properdin as potential treatments for acute inflammatory...our intellectual property around anti-properdin agents and their promising utility as...
GLIATECH, ABGENIX IN PROPERDIN ANTIBODY DEAL FOR UP TO $40M.(Brief Article)
Magazine article from: BIOWORLD Today; 11/5/2001; ; 700+ words ; ...license to develop and commercialize anti-properdin antibody therapies for all indications...monoclonal antibody therapies against properdin, a complement protein. Gliatech gets...technology to make antibodies targeted at the properdin antigen. Gliatech had been working in...
California Inventors Develop Anti-Properdin Antibodies
News Wire article from: US Fed News Service, Including US State News; 9/22/2008; 396 words ; ...Calif., and Gerardo Zapata of San Mateo, Calif., have developed antibodies, and in particular, antibodies specific for properdin, the U.S. Patent & Trademark Office announced. The inventors were issued U.S. Patent No. 7,423,128 on Sept...
Research from Leiden University, Department of Nephrology provides new data on kidneys.
Newspaper article from: Biotech Week; 12/17/2008; 700+ words ; ...activation by tubular cells is mediated by properdin binding,' is now available. "Activation...activation indicate a key role for properdin in the initiation of an alternative pathway. We hypothesized that properdin serves as a focal point for complement...
New discovery on role of vital protein that fights meningitis.
Newspaper article from: Health & Medicine Week; 5/19/2008; 700+ words ; ...The study also reveals that the same protein, Properdin udiscovered only half a century ago- can also harm...the first line immune defence, a protein called Properdin. "Properdin deficiency in families, though rare, predisposes...
Abgenix Licenses From Gliatech Antibody Product Candidates for Cardiovascular and Inflammatory Diseases; IND Planned for 2002.
Business Wire; 11/2/2001; 700+ words ; ...therapies against the complement protein properdin as potential treatments for cardiovascular...application to the FDA for an anti-properdin antibody product candidate next year...license to develop and commercialize anti-properdin antibody therapies for all indications...
Love, honor, draw blood ; At this wedding, the newlyweds and their guests all rolled up their sleeves to help find a genetic killer.
Newspaper article from: Sunday News Lancaster, PA; 9/12/2004; ; 700+ words ; ...their mother, said Morton, and that is properdin deficiency. The clinic sent the blood of the surviving cousin to be tested for properdin and found that it was missing. Once the clinic knew that properdin deficiency was the risk factor, said...
Monoclonal Antibody Has Potential in Reducing Heart Attack Damage.
Newspaper article from: Immunotherapy Weekly; 8/9/2000; 700+ words ; ...has previously shown that its anti-properdin MAbs effectively block complement activation...In the most recent study, an anti-properdin MAb was shown to significantly reduce...These data further suggest that an anti-properdin MAb may also have clinical utility in...
Gliatech's Monoclonal Antibody Indicates Potential in Myocardial Ischemia.
PR Newswire; 7/27/2000; 700+ words ; ...has previously shown that its anti-properdin MoAbs effectively block complement activation...In the most recent study, an anti- properdin MoAb was shown to significantly reduce...data further suggests that an anti-properdin MoAb may also have clinical utility in...
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