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^sup 123^I-ITdU-Mediated Nanoirradiation of DNA Efficiently Induces Cell Kill in HL60 Leukemia Cells and in Doxorubicin-, [beta]-, or [gamma]-Radiation-Resistant Cell Lines
The Journal of Nuclear Medicine; 6/1/2007; Reske, Sven N; Deisenhofer, Sandra; Glatting, Gerhard; Zlatopolskiy, Boris D; Et al; 5405 words
; ... 3:110-121. 11. Dupertuis Y, Vazquez M, March J, et al. Fluorodeoxyuridine improves imaging of human glioblastoma xenografts with ... Genton CS, Schaffland AO, Dupertuis YM, Buchegger F. Short fluorodeoxyuridine exposure of different human glioblastoma lines induces ...
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5-[^sup 123^I/^sup 125^I]Iodo-2'-Deoxyuridine in Metastatic Lung Cancer: Radiopharmaceutical Formulation Affects Targeting
The Journal of Nuclear Medicine; 5/1/2005; Semnani, Elham Safaie; Wang, Ketai; Adelstein, S James; Kassis, Amin I; 5149 words
; ... sup 125^I-IUdR uptake occurs (7). Fluorodeoxyuridine (FUdR), a thymidylate synthetase ... YM, Vazquez M, Mach J-P, et al. Fluorodeoxyuridine improves imaging of human glioblastoma ... and gamma radiation dosimetry for fluorodeoxyuridine-enhanced tumour proliferation scinligraphy ...
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Local Glutathione Redox Status Does Not Regulate Ileal Mucosal Growth after Massive Small Bowel Resection in Rats1
The Journal of Nutrition; 2/1/2007; Tian, Junqiang; Washizawa, Naohiro; Gu, Li H; Levin, Marc S; Et al; 5465 words
; ... outlined previously by Martensson et al. (17). Rats were injected i.p. with 120 mg/kg 5-BrdU (40 g/L 5-BrdU and 4 g/L 5-fluorodeoxyuridine) 90 min before being killed by exsanguination. In Experiment 2, rats (229 2 g) were assigned by weight to 3 groups ... Natl Acad Sci USA. 1990;87:1715-9. 31. Aw TY. Cellular redox: a ...
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Integration of Chloroplast Nucleic Acid Metabolism into the Phosphate Deprivation Response in Chlamydomonas reinhardtii(OA)
Plant Cell; 3/1/2007; Yehudai-Resheff, Shlomit; Zimmer, Sara L; Komine, Yutaka; Stern, David B; 10734 words
; ... were reexamined with cells grown in the presence of 5-fluorodeoxyuridine, which inhibits cpDNA replication in Chlamydomonas (Wurtz ... chloroplast gene transmission In Chlamydomonas reinhardtii by 5-fluorodeoxyuridine. Proc. Natl. Acad. Sci. USA 74: 4552-4556. Wykoff, D.D ...
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Synthesis and Evaluation of 2'-Deoxy-2'-^sup 18^F-Fluoro-5-Fluoro-1-[beta]-D-Arabinofuranosyluracil as a Potential PET Imaging Agent for Suicide Gene Expression
The Journal of Nuclear Medicine; 12/1/2004; Alauddin, Mian M; Shahinian, Antranic; Park, Ryan; Tohme, Michel; Et al; 5084 words
; ... earlier that FFAUMP forms a stable complex with TS and methylene tetrahydrofolate in a manner analogous to that for 5-fluorodeoxyuridine monophosphate, which could be isolated and hydrolyzed by a base. Our observation is consistent with the earlier report ...
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Pump Removal in Infected Patients with Hepatic Chemotherapy Pumps: When Is It Necessary?
The American Surgeon; 10/1/2006; Roybal, Jonathan J; Feliberti, Eric C; Rouse, Layla; Wagman, Lawrence D; 3043 words
; ... Chang AE, Schneider PD, Sugarbaker PH, et al. A prospective randomized trial of regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases. Ann Surg 1987;206:685-93. 8. Faynsod M, Wagman LD, Longmate ...
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Predictive Markers in Breast and Other Cancers: A Review
Clinical Chemistry; 3/1/2005; Duffy, Michael J; 8179 words
; ... chemotherapeutic agents, including the fluoropyrimidines, 5-FU and 5-fluorodeoxyuridine, and the antifolate, tomudex. 5-FU, in particular, is ... 4, 54). To inhibit TS, 5-FU is first converted to 5-fluorodeoxyuridine monophosphate, which forms a covalent complex with TS ...
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Hepatic artery chemotherapy in the management of colorectal metastases.(Clinical report)
Baylor University Medical Center Proceedings; 10/1/2002; Stratmann, Stacy L.; 3593 words
; ... Botet J, Oderman P. Intrahepatic or systemic infusion of fluorodeoxyuridine in patients with liver metastases from colorectal carcinoma ... randomized trial of regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases ...
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A Complication-Free Course Ensures a Survival Advantage in Patients After Regional Therapy for Metastatic Colorectal Cancer
The American Surgeon; 6/1/2006; Osborne, Dana; Pappas, Effie; Alexander, Gerald; Boe, Brian; Et al; 3166 words
; ... commonly used, fluorouracil and fluorodeoxyuridine (FUDR), have steep dose-response ... Intrahepatic or systemic infusion of fluorodeoxyuridine in patients with liver metastases ... regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of ...
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Researcher, 14, wows audience
Chicago Sun-Times; 10/8/1988; 378 words
; ... next-door neighbor and research partner, cancer expert Dr. Glenn Tisman. The pair worked on a plan to combine a chemical, 5-Fluorodeoxyuridine - 5FUdR, for short - with a vitamin derivative in an effort to kill cancer cells, the teenager said. Both said the plan ...
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