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cysteine
cysteine , organic compound, one of the 20 amino acids commonly found in animal proteins . Only the l -stereoisomer participates in the biosynthesis of mammalian protein. It is particularly abundant in the proteins of hair, hooves, and the keratin of the skin. Cysteine's importance is related to the presence of a sulfur-containing thiol group in its side chain. This group participates in the catalytic reactions of certain enzymes, such as that of papain, the enzyme from papaya latex used to make commercial meat tenderizers. The thiol group of one cysteine residue is capable of combining with the thiol group of another to form a disulfide bridge, either linking two peptide chains together, as in the case of insulin , or causing a single peptide chain to fold back on itself, making a loop. This latter effect on the secondary structure of proteins is evidently of great importance in maintaining the proper configuration of both structural proteins and enzymes. Two cysteine molecules linked together by a disulfide linkage make up the amino acid cystine, often occurring as a separate entry in lists of common amino acids. A major complication of cystinuria, an inherited metabolic disease, one of whose symptoms is a twentyfold to thirtyfold increase in urinary excretion of cystine, is the precipitation of this relatively insoluble amino acid in the kidney, impairing its function. A similar sort of renal failure often accompanies cystinosis, another inherited disease. Cystine was isolated from a urinary calculus in 1810 and from horn tissue in 1899. The reduction of cystine to cysteine was reported in 1884, and the structures of the two amino acids were proved by chemical synthesis in 1903-4. Neither cysteine nor cystine is essential to the diet of man; cystine and cysteine are interconvertible, and cysteine is made in the body from serine and methionine . |
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"cysteine." The Columbia Encyclopedia, 6th ed.. 2008. Encyclopedia.com. 11 Feb. 2012 <http://www.encyclopedia.com>. "cysteine." The Columbia Encyclopedia, 6th ed.. 2008. Encyclopedia.com. (February 11, 2012). http://www.encyclopedia.com/doc/1E1-cysteine.html "cysteine." The Columbia Encyclopedia, 6th ed.. 2008. Retrieved February 11, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1E1-cysteine.html |
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cysteine
cysteine A non‐essential amino acid, but nutritionally important since it spares the essential amino acid methionine. In addition to its role in protein synthesis, cysteine is important as the precursor of taurine, in formation of coenzyme A from the vitamin pantothenic acid and in formation of the tripeptide glutathione. It is used as a dough ‘improver’ in baking. See also cystine.
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DAVID A. BENDER. "cysteine." A Dictionary of Food and Nutrition. 2005. Encyclopedia.com. 11 Feb. 2012 <http://www.encyclopedia.com>. DAVID A. BENDER. "cysteine." A Dictionary of Food and Nutrition. 2005. Encyclopedia.com. (February 11, 2012). http://www.encyclopedia.com/doc/1O39-cysteine.html DAVID A. BENDER. "cysteine." A Dictionary of Food and Nutrition. 2005. Retrieved February 11, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O39-cysteine.html |
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cysteine
cysteine (sis-ti-een) n. a sulphur-containing amino acid that is an important constituent of many enzymes.
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"cysteine." A Dictionary of Nursing. 2008. Encyclopedia.com. 11 Feb. 2012 <http://www.encyclopedia.com>. "cysteine." A Dictionary of Nursing. 2008. Encyclopedia.com. (February 11, 2012). http://www.encyclopedia.com/doc/1O62-cysteine.html "cysteine." A Dictionary of Nursing. 2008. Retrieved February 11, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O62-cysteine.html |
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cysteine
cysteine An aliphatic, polar (see POLAR MOLECULE), alpha-amino acid that contains a sulphydryl group.
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MICHAEL ALLABY. "cysteine." A Dictionary of Plant Sciences. 1998. Encyclopedia.com. 11 Feb. 2012 <http://www.encyclopedia.com>. MICHAEL ALLABY. "cysteine." A Dictionary of Plant Sciences. 1998. Encyclopedia.com. (February 11, 2012). http://www.encyclopedia.com/doc/1O7-cysteine.html MICHAEL ALLABY. "cysteine." A Dictionary of Plant Sciences. 1998. Retrieved February 11, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O7-cysteine.html |
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cysteine
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MICHAEL ALLABY. "cysteine." A Dictionary of Zoology. 1999. Encyclopedia.com. 11 Feb. 2012 <http://www.encyclopedia.com>. MICHAEL ALLABY. "cysteine." A Dictionary of Zoology. 1999. Encyclopedia.com. (February 11, 2012). http://www.encyclopedia.com/doc/1O8-cysteine.html MICHAEL ALLABY. "cysteine." A Dictionary of Zoology. 1999. Retrieved February 11, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O8-cysteine.html |
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cysteine
cysteine See amino acid.
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"cysteine." A Dictionary of Biology. 2004. Encyclopedia.com. 11 Feb. 2012 <http://www.encyclopedia.com>. "cysteine." A Dictionary of Biology. 2004. Encyclopedia.com. (February 11, 2012). http://www.encyclopedia.com/doc/1O6-cysteine.html "cysteine." A Dictionary of Biology. 2004. Retrieved February 11, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O6-cysteine.html |
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