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Binding of actinomycin D to single-stranded DNA of sequence motifs d(TGTCT(n)G) and d(TGT(n)GTCT)
Biophysical Journal; 1/1/2003; Chen, Fu-Ming; Sha, Feng; Chin, Ko-Hsin; Chou, Shan-Ho; 1642 words
; ... CGTCGTCG) had led to the finding that actinomycin D (ACTD) binds strongly to d(TGTCATTG ... and found to bind well. INTRODUCTION Actinomycin D (ACTD) is an extensively studied antitumor ... systematic binding studies of 7-amino-actinomycin D (7-AM-ACTD) with single-stranded oligomers ...
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Guidant stops study evaluating actinomycin-D drug eluting stent.
Biomedical Materials; 4/1/2002; 210 words
; ... evaluating a drug eluting stent system using actinomycin-D. Preliminary results of the study indicate that actinomycin-D is not effective in preventing restenosis and patients treated with actinomycin-D eluting stents have an unacceptably high ...
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Late recurrence in children with Wilms' tumor
The Turkish Journal of Pediatrics; 4/1/2007; Büyükpamukçu, Münevver; Köksal, Yavuz; Varan, Ali; Atahan, Lale; Et al; 2565 words
; ... which included vincristine and actinomycin-D. Abdominal radiotherapy was performed ... protocols were as follows: vincristine, actinomycin-D, adriamycin, and cyclophosphamide in two patients; vincristine, actinomycin-D, and epirubicin in one patient ...
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Reversal of multidrug resistance in cancer cells by Rhizoma Alismatis extract.(Drug overview)
Phytomedicine: International Journal of Phytotherapy & Phytopharmacology; 2/1/2007; Fong, W.-F. Wang, C. Zhu, G.-Y. Leung, C.-H. Yang, M.-S. Cheung, H.-Y.; 2985 words
; ... drugs that are Pgp substrates including actinomycin D, puromycin, paclitaxel, vinblastine ... from Sigma Chemical (St. Louise, US); Actinomycin D from Acros Organics (New Jersey, US ... the anticancer drugs tested including actinomycin D, puromycin, paclitaxel, vinblastine ...
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Transforming Growth Factor-[beta] Induces Airway Smooth Muscle Hypertrophy
American Journal of Respiratory Cell and Molecular Biology; 2/1/2006; Goldsmith, Adam M; Bentley, J Kelley; Zhou, Limei; Jia, Yue; Et al; 6191 words
; ... presence of the transcriptional inhibitor actinomycin D, evidence that translational control ... presence of the transcriptional inhibitor actinomycin D. TGF-β induced the phosphorylation ... muscle actin mRNA after incubation with actinomycin D, a transcriptional inhibitor (5 mg ...
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MECHANISMS OF MICROVASCULAR WOUND REPAIR I. ROLE OF MITOSIS, OXYGEN TENSION, AND I-KAPPA B
In Vitro Cellular & Developmental Biology; 11/1/2006; Chaudhuri, Vaishali; Potts, Brian R; Karasek, Marvin A; 4307 words
; ... not reduce reendothelialization and both actinomycin D and cycloheximide inhibited repair by ... yellow CH dipotassium salt, mitomycin c, actinomycin-D, and cyhcloheximide, PDTC, NAC (Sigma ... preincubated with mitomycin-C (10 μg/ml), actinomycin D (3 ng/ml), and cycloheximide (10 μ..transcription ...
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Cell-Free Plasma DNA: A Marker for Apoptosis during Hemodialysis
Clinical Chemistry; 3/1/2006; Atamaniuk, Johanna; Ruzicka, Katharina; Stuhlmeier, Karl M; Karimi, Alireza; Et al; 2472 words
; ... with annexin V expression and 7-amino-actinomycin D (7AAD) nuclear staining of blood leukocytes ... expression in combination with 7-amino-actinomycin D (7AAD) nuclei staining (6). In early ... Dead cell discrimination with 7-amino-actinomycin d in combination with dual color immune-fluorescen ...
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Glucocorticoid Regulation of Human Pulmonary Surfactant Protein-B mRNA Stability Involves the 3'-Untranslated Region
American Journal of Respiratory Cell and Molecular Biology; 4/1/2008; Huang, Helen W; Bi, Weizhen; Jenkins, Gaye N; Alcorn, Joseph L; 8053 words
; ... transcription, the transcription inhibitor actinomycin D (10 g/ml, #A9415; Sigma) (21) was ... isolated at various times after addition of actinomycin D and subjected to real-time quantitative ... sup -7^ M) for 48 hours, at which time actinomycin D was added to inhibit transcription ...
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Selenium influences the turnover of selenocysteine tRNA([Ser]Sec) in Chinese hamster ovary cells
The Journal of Nutrition; 7/1/2002; Jameson, Ruth R; Carlson, Bradley A; Butz, Michael; Esser, Karyn; Et al; 1808 words
; ... treated with the transcription inhibitor, actinomycin D, and tRNA[srl'sc levels were determined ... tRNA. Inhibition of transcription with actinomycin D resulted in a relative increase in ... of protein synthesis in CHO cells by actinomycin D: lesion occurs after 40S initiation ...
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Interleukin-13 and Interleukin-4 Induce Vascular Endothelial Growth Factor Release from Airway Smooth Muscle Cells: Role of Vascular Endothelial Growth Factor Genotype
American Journal of Respiratory Cell and Molecular Biology; 2/1/2006; Faffe, Débora S; Flynt, Lesley; Bourgeois, Kerri; Panettieri, Reynold A Jr; Shore, Stephanie A; 5269 words
; ... real-time PCR, mRNA stability using actinomycin D, and promoter activity with a VEGF-promot ... Cells were treated with IL-4 for 6 h. Actinomycin D (Sigma, St. Louis, MO) was added ... treated or untreated with IL-4 for 6 h. Actinomycin D was added to the cells to inhibit ...
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