Joseph Leonard Goldstein

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Joseph Leonard Goldstein

Joseph Leonard Goldstein , 1940-, American molecular geneticist, b. Sumter, S.C., M.D. Univ. of Texas at Dallas, 1966. He worked as a biomedical researcher at the National Heart Institute (1968-70) and Washington Univ. (1970-72) before returning to the Southwestern Medical School of the Univ. of Texas at Dallas as professor. Goldstein and colleague Michael S. Brown researched cholesterol metabolism and discovered that human cells have low-density lipoprotein (LDL) receptors that extract cholesterol from the bloodstream. The lack of sufficient LDL receptors is a major cause of cholesterol-related diseases. In 1985, Goldstein and Brown were jointly awarded the Nobel Prize in Physiology or Medicine.

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Goldstein, Joseph L.

A Dictionary of Food and Nutrition | 2005 | | Â© A Dictionary of Food and Nutrition 2005, originally published by Oxford University Press 2005. (Hide copyright information) Copyright

Goldstein, Joseph L. (born 1940) American physician; Nobel Prize 1985, jointly with Brown, for discoveries concerning the regulation of cholesterol metabolism.

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