Biochemistry: Biographies

The Columbia Encyclopedia, 6th ed. A Dictionary of Food and Nutrition Further reading

Joseph Leonard Goldstein

The Columbia Encyclopedia, 6th ed. | 2011 | Copyright

Joseph Leonard Goldstein , 1940–, American molecular geneticist, b. Sumter, S.C., M.D. Univ. of Texas at Dallas, 1966. He worked as a biomedical researcher at the National Heart Institute (1968–70) and Washington Univ. (1970–72) before returning to the Southwestern Medical School of the Univ. of Texas at Dallas as professor. Goldstein and colleague Michael S. Brown researched cholesterol metabolism and discovered that human cells have low-density lipoprotein (LDL) receptors that extract cholesterol from the bloodstream. The lack of sufficient LDL receptors is a major cause of cholesterol-related diseases. In 1985, Goldstein and Brown were jointly awarded the Nobel Prize in Physiology or Medicine.

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Goldstein, Joseph L.

A Dictionary of Food and Nutrition | 2005 | | Copyright

Goldstein, Joseph L. (born 1940) American physician; Nobel Prize 1985, jointly with Brown, for discoveries concerning the regulation of cholesterol metabolism.

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DAVID A. BENDER. "Goldstein, Joseph L." A Dictionary of Food and Nutrition. 2005. Encyclopedia.com. 31 May. 2012 <http://www.encyclopedia.com>.

DAVID A. BENDER. "Goldstein, Joseph L." A Dictionary of Food and Nutrition. 2005. Encyclopedia.com. (May 31, 2012). http://www.encyclopedia.com/doc/1O39-GoldsteinJosephL.html

DAVID A. BENDER. "Goldstein, Joseph L." A Dictionary of Food and Nutrition. 2005. Retrieved May 31, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O39-GoldsteinJosephL.html

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