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César Milstein
César Milstein 1927–2002, Anglo-Argentine immunologist, Ph.D. Cambridge, 1960. He worked (1961–63) at the National Institute of Microbiology, Buenos Aires, but following a military coup he resigned and returned to Cambridge, where he joined the staff of the Medical Research Council Laboratory of Molecular Biology, serving as its deputy director from 1988 to 1995, when he retired. In 1975, with Georges Köhler , he developed the hybridoma technique for producing monoclonal antibodies , pure, mass-produced antibodies that recognize only one antigen (see immunity ). Their method for monoclonal antibody production has since been adopted universally, and such antibodies are used in laboratory research, in medical diagnostics, and in medical treatments to neutralize bacterial toxins. In 1984, Milstein (with Köhler and Niels K. Jerne ) shared the Nobel Prize in Physiology or Medicine. |
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"César Milstein." The Columbia Encyclopedia, 6th ed.. 2011. Encyclopedia.com. 31 May. 2012 <http://www.encyclopedia.com>. "César Milstein." The Columbia Encyclopedia, 6th ed.. 2011. Encyclopedia.com. (May 31, 2012). http://www.encyclopedia.com/doc/1E1-MilsteinC.html "César Milstein." The Columbia Encyclopedia, 6th ed.. 2011. Retrieved May 31, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1E1-MilsteinC.html |
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Milstein, César
Milstein, César (1927–2002) British molecular biologist and immunologist, b. Argentina. He shared the 1984 Nobel Prize in physiology or medicine for helping to develop antibodies that can be commercially produced for drugs and diagnostic tests. In 1975, Milstein and the German immunochemist Georges Köhler developed a technique for cloning monoclonal antibodies (MABs) that combat diseases by targeting their sites.
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"Milstein, César." World Encyclopedia. 2005. Encyclopedia.com. 31 May. 2012 <http://www.encyclopedia.com>. "Milstein, César." World Encyclopedia. 2005. Encyclopedia.com. (May 31, 2012). http://www.encyclopedia.com/doc/1O142-MilsteinCsar.html "Milstein, César." World Encyclopedia. 2005. Retrieved May 31, 2012 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O142-MilsteinCsar.html |
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