Antabuse

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Antabuse

Antabuse , trade name for the drug tetraethylthiuram disulfide, used in the treatment of alcoholism . Also called sulfiram, Antabuse is nontoxic, but it alters the metabolism of alcohol in the body, making it impossible for one who is taking the drug to drink without experiencing severe discomfort. When alcohol is present the drug increases the concentration of acetaldehyde in the body, causing symptoms resembling those of a bad hangover: the individual feels hot, the face becomes flushed, the neck and head throb, and nausea, vomiting, and headache may follow. Small quantities of alcohol, such as from food sauces and cough medicines, and even inhaled traces from shaving lotions and varnishes, may induce the same symptoms. The drug Temposil, or citrated calcium carbamide, has the same function as Antabuse, but is weaker and safer. The therapeutic use of Antabuse was discovered in the 1930s when workers exposed to tetraethylthiuram disulfide, a chemical used in the rubber industry, became ill after drinking alcoholic beverages.

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Antabuse

A Dictionary of Food and Nutrition | 2005 | | Â© A Dictionary of Food and Nutrition 2005, originally published by Oxford University Press 2005. (Hide copyright information) Copyright

Antabuse Trade name for the drug disulfiram, used in the treatment of alcoholism. It inhibits the further metabolism of acetaldehyde arising from the metabolism of alcohol, and so causes headache, nausea, vomiting, and palpitations if alcohol is consumed.

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DAVID A. BENDER. "Antabuse." A Dictionary of Food and Nutrition. 2005. Encyclopedia.com. 9 Jul. 2009 <http://www.encyclopedia.com>.

DAVID A. BENDER. "Antabuse." A Dictionary of Food and Nutrition. 2005. Encyclopedia.com. (July 9, 2009). http://www.encyclopedia.com/doc/1O39-Antabuse.html

DAVID A. BENDER. "Antabuse." A Dictionary of Food and Nutrition. 2005. Retrieved July 09, 2009 from Encyclopedia.com: http://www.encyclopedia.com/doc/1O39-Antabuse.html

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Antabuse

A Dictionary of Nursing | 2008 | Â© A Dictionary of Nursing 2008, originally published by Oxford University Press 2008. (Hide copyright information) Copyright

Antabuse (ant-ă-bews) n. see disulfiram.

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