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Monoamine oxidase
monoamine oxidase (MAO) (mon-oh-ay-meen) n. an enzyme that catalyses the oxidation of a large variety of monoamines, including adrenaline, noradrenaline, and serotonin. Monoamine oxidase is found in most tissues, particularly the liver and nervous system. See also MAO inhibitor.... Read more |
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tyramine
tyramine A biologically active amine, derived from tyrosine, that mimics the effects of adrenaline, causing increased heart activity and raising blood pressure. It occurs naturally in body tissues and can also be found in ergot, mistletoe, putrefied animal tissue, and cheese. Certain antidepressant... Read more |
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Phenelzine
Phenelzine Definition Phenelzine is classified as a monoamine oxidase (MAO) inhibitor. In the United States, phenelzine is sold under the brand name Nardil. Purpose Phenelzine is used to treat certain types of serious depression and severe depression complicated by severe anxiety... Read more |
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ACE inhibitor
ACE inhibitor or angiotensin-converting enzyme inhibitor , drug used to reduce elevated blood pressure (see hypertension ), to treat congestive heart failure , and to alleviate strain on hearts damaged as a result of a heart attack (see infarction ). ACE inhibitors block production of an... Read more |
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antidepressant
antidepressant any of a wide range of drugs used to treat psychic depression . They are given to elevate mood, counter suicidal thoughts, and increase the effectiveness of psychotherapy . Before the introduction of such drugs in the late 1950s, most patients with major depression had no recourse... Read more |
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cholinesterase
Cholinesterase inhibitors Definition Cholinesterase inhibitors are a group of drugs prescribed to treat symptoms resulting from the early and middle stages of Alzheimer disease . Purpose Cholinesterase inhibitors are drugs that block the activity of an enzyme in the brain called cholinesterase.... Read more |
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protease inhibitor
protease inhibitor , any of a class of drugs that interfere with replication of the AIDS virus ( HIV ), by blocking an enzyme (protease) necessary in the late stages of its reproduction. Clinical trials of the protease inhibitor indinavir have shown it to be especially beneficial in combination... Read more |
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COX-2 inhibitor
COX-2 inhibitor n. an anti-inflammatory drug (see NSAID) that selectively blocks the action of the enzyme cyclo-oxygenase 2 (COX-2), which mediates the production of prostaglandin at sites of inflammation, especially in joints; such drugs are less likely than nonselective NSAIDs to cause... Read more |
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Imatinib mesylate
Imatinib mesylate Definition Imatinib mesylate is an enzyme inhibitor used for cancer therapy. Imatinib mesylate is also known as STI571 and is sold under the brand name, Gleevec. It was given the name STI571 during early development. STI stands for signal transduction... Read more |
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catalyst
catalyst substance that can cause a change in the rate of a chemical reaction without itself being consumed in the reaction; the changing of the reaction rate by use of a catalyst is called catalysis. Substances that increase the rate of reaction are called positive catalysts or, simply,... Read more |
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New MAO Inhibitors Offer Reversibility, Selectivity. (MAO Inhibitors...
...contrast to classic monoamine oxidase (MAO) inhibitors...inhibit intestinal monoamine oxidase A, we get...reversible inhibitors of monoamine oxidase A are free...reversible MAO-A (RIMA) inhibitors is moclobemide, already...displace the reversible inhibitor ... |
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Unraveling Varied Roles for MAO. (MAO Inhibitors Revisited).(monoamine...
...biology and activity of monoamine oxidases (MAOs) has provided...selectivity of MAO inhibitors. Overlap in Specifications...patient and irreversible inhibitor and discontinue treatment...contrast, reversible MAO inhibitors do not covalently bind...Irreversible MAO inhibitors include ... |
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The older antidepressants. (Rx Primer).(monoamine oxidase inhibitors)(Brief...
...the tricyclic and tetracyclic family and the monoamine oxidase inhibitors. They are still used world wide, particularly...poor response to the newer antidepressants. The monoamine oxidase inhibitors (MAO-I) are named for their effect... |
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Transdermal Selegiline Could Spur Increased Use of MAO Inhibitors. (MAO...
...Reformulation of the classic monoamine oxidase (MAO) inhibitor selegiine into a transdermal...spar increased use of MAO inhibitors in the treatment of major...remarkable, considering that monoamine oxidase inhibitors, as a group... |
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Despite Restrictions, MAOIs Are Best Bet for Anxious Teens.(monoamine oxidase...
...and other precautions should not deter use of monoamine oxidase inhibitors in adolescent patients, Dr. Ginny Gerbino...the American Society of Adolescent Psychiatry. Monoamine oxidase inhibitors (MAOIs) are the granddaddy of antidepressants... |
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MAO Inhibitors Enjoy Resurgence of Interest, Use. (MAO Inhibitors...
...will benefit from therapy, monoamine oxidase (MAO) inhibitors have experienced a resurgence...in selected patients. MAO inhibitors have much clearer indications...of the drugs, use of MAO inhibitors could expand even further... |
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Knowledge of Mechanisms Continues to Emerge. (MAO Inhibitors...
...antidepressant mechanisms of monoamine oxidase (MAO) inhibitors, although not completely...norepinephrine, MAO inhibitors rapidly and robustly...clinical effect of MAO inhibitors. The monoaminergic...according to the type of inhibitor used. Dr Blier... |
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Introduction. (MAO Inhibitors Revisited).(monoamine oxidase inhibitors)
...effective antidepressant agents, monoamine oxidase (MAO) inhibitors frequently have been relegated...unquestioned efficacy, MAO inhibitors are used in only a small percentage...prompted a re-evaluation of MAO inhibitors and their role in the treatment... |
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WIPO PUBLISHES PATENT OF VARINEL FOR "NEUROPROTECTIVE AND NEURO-RESTORATIVE...
...published on Feb. 16. Title of the invention: "NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF." Applicants: VARINEL INC (US). Inventors: Vincent R. Zurawski Jr. (US), David... |
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Depression.(BLACK HEALTH & Fitness section: Health Hotline)(Vagal-nerve...
...medication, including selective serotonin reuptake inhibitors (SSRIs), which act on serotonin only, and tricyclics...which act on both serotonin and norepinenephrine. Monoamine oxidase inhibitors (MAOIs), another antidepressant, is less frequently... |