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Topics related to "hemoglobin"

hemoglobin
hemoglobin , respiratory protein found in the red blood cells (erythrocytes) of all vertebrates and some invertebrates. A hemoglobin molecule is composed of a protein group, known as globin, and four heme groups, each associated with an iron atom. In the lungs, each iron atom combines reversi... Read more
sickle cell disease
sickle cell disease or sickle cell anemia, inherited disorder of the blood in which the oxygen-carrying hemoglobin pigment in erythrocytes (red blood cells) is abnormal. This "hemoglobin-S" crystallizes in small capillaries, where the concentration of oxygen in the blood is low (but suffi... Read more
anemia
anemia , condition in which the concentration of hemoglobin in the circulating blood is below normal. Such a condition is caused by a deficient number of erythrocytes (red blood cells), an abnormally low level of hemoglobin in the individual cells, or both these conditions simultaneously. Regardless... Read more
Max Ferdinand Perutz
Max Ferdinand Perutz 1914-2002, British molecular biologist, b. Vienna. One of the pioneers in the field of molecular biology , Perutz studied chemistry at the Univ. of Vienna (1932-36) and then at Cambridge (Ph.D. 1940), where he began a lifelong association with Cavendish Laboratory. There he st... Read more
blood count
blood count method for determining the number of red (erythrocytes) and white (leukocytes) blood cells in a certain volume of blood. This test can be used as a preliminary step in diagnosing some diseases. Leukemia, for instance, causes an increase in the white blood cell count, while a decrease in... Read more
pigmentation
pigmentation name for the coloring matter found in certain plant and animal cells and for the color produced thereby. Pigmentation occurs in nearly all living organisms. Almost all plants synthesize their own pigments; animals either derive pigments from plant foods or synthesize them themselves. ... Read more
chelating agents
chelating agents . Certain organic compounds are capable of forming coordinate bonds (see chemical bond ) with metals through two or more atoms of the organic compound; such organic compounds are called chelating agents. The compound formed by a chelating agent and a metal is called a chelate. A ch... Read more
cyanosis
cyanosis , bluish coloration of the skin, mucous membranes, and nailbeds, resulting from a lack of oxygenated hemoglobin in the blood. It is a symptom of many disorders, including various pulmonary and heart diseases and many congenital heart defects (see blue baby ). Cyanosis that is caused by slo... Read more
glycine
glycine , organic compound, one of the 20 amino acids commonly found in animal proteins. Glycine is the only one of these amino acids that is not optically active, i.e., it does not have d - and l -stereoisomers. It is structurally the simplest of the α-amino acids, having merely a hyd... Read more
hemolysis
hemolysis , destruction of red blood cells in the bloodstream. Although new red blood cells, or erythrocytes, are continuously created and old ones destroyed, an excessive rate of destruction sometimes occurs. The dead cells, in sufficiently large numbers, overwhelm the organ that destroys them, the... Read more

Encyclopedia entries related to "hemoglobin"

Hemoglobin Test
Encyclopedia entry from: Gale Encyclopedia of Surgery: A Guide for Patients and Caregivers Hemoglobin test Definition Hemoglobin is a protein inside red blood cells that carries oxygen. A hemoglobin test reveals how much hemoglobin is in a person's blood. This information can be used to help physician's diagnose and monitor anemia...
Fetal Hemoglobin Test
Encyclopedia entry from: Gale Encyclopedia of Children's Health: Infancy through Adolescence Fetal hemoglobin test Definition A fetal hemoglobin test (Hgb electrophoresis) measures the level of fetal hemoglobin (Hemoglobin F or HbF) in the blood of infants and children. It can also be measured in adults, though is more typically needed...
Hemoglobin
Encyclopedia entry from: The Gale Encyclopedia of Science Hemoglobin Hemoglobin is a protein formed of two subunits (alpha and beta) that are found...distinctive color that inspired their name. The presence of iron enables hemoglobin to alternatively bind oxygen and carbon dioxide. As blood is pumped...
Glycosylated Hemoglobin Test
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. Glycosylated Hemoglobin Test Definition Glycosylated hemoglobin is a test that indicates how much sugar has been in...level is at the time of the test. The glycosylated hemoglobin test reveals how close to normal it has been during...
Hemoglobin Electrophoresis
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. Hemoglobin Electrophoresis Definition Hemoglobin electrophoresis (also called Hgb electrophoresis), is a test that measures the different types of hemoglobin in the blood. The method used is called electrophoresis...
Glycosylated Hemoglobin
Encyclopedia entry from: Encyclopedia of Public Health GLYCOSYLATED HEMOGLOBIN The red blood cells of all individuals contain hemoglobin, which is responsible for carrying oxygen through the bloodstream. When hemoglobin combines with glucose (sugar), a molecule called glycosylated hemoglobin...
hemoglobin
Book article from: The Columbia Encyclopedia, Sixth Edition hemoglobin , respiratory protein found in the red...vertebrates and some invertebrates. A hemoglobin molecule is composed of a protein group...reversibly with a molecule of oxygen. Each hemoglobin molecule also has attached a single...
Red Blood Cell Indices
Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. ...size and oxygen-carrying protein (hemoglobin) content of red blood cells. The indices...red blood cells that contain enough hemoglobin to carry sufficient oxygen to all the...marrow. Inherited disorders affecting hemoglobin, severe reactions to blood transfusions...
Sickle Cell Anemia
Encyclopedia entry from: The Gale Encyclopedia of Science ...in one of the component proteins of hemoglobin. The component protein, or globin...contains the substitution is defective. Hemoglobin molecules constructed with such proteins...to one another, forming strands of hemoglobin within the red blood cells. The cells...
Sickle Cell Disease
Encyclopedia entry from: Encyclopedia of Public Health ...valine for glutamic acid in the sixth amino acid of the chain, producing a hemoglobin, designated hemoglobin S, that has less solubility than does normal hemoglobin A. Inheriting one gene for hemoglobin S, together with a normal gene, results...

Dictionary entries related to "hemoglobin"

hemoglobin
Book article from: A Dictionary of Food and Nutrition hemoglobin American spelling of haemoglobin ; similarly, hematin = haematin, heme = haem, hemosiderin = haemosiderin.
Hoppe-Seyler, Felix
Dictionary entry from: Complete Dictionary of Scientific Biography ...researches on the substance he called hemoglobin, the absorption spectrum of which he...years Hoppe-Seyler demonstrated that hemoglobin binds oxygen loosely to form oxyhemoglobin...researches showed that treatment of hemoglobin with acid produces a material he named...
Haldane, John Scott
Dictionary entry from: Complete Dictionary of Scientific Biography ...he showed that carbon monoxide binds hemoglobin, preventing it from serving as the...Other work was more solid. Studies on hemoglobin dissociation showed very clearly the...in which the degree of oxygenation of hemoglobin affects the uptake of carbon dioxide...
Barcroft, Joseph
Dictionary entry from: Complete Dictionary of Scientific Biography ...to calculate the rate of exchange, for he found that the hemoglobin in the venous blood was more concentrated because some of...venous blood, rather than the percentage saturation of the hemoglobin with oxygen, which most directly determined the amount of...
Bunge, Gustav von
Dictionary entry from: Complete Dictionary of Scientific Biography ...food and resorbed from it might be utilized to synthesize hemoglobin in the organism. Accordingly, Bunge attempted ot isolate...bound iron can be resorbed and utilized for the building up of hemoglobin. Iron-rich vegetables similarly have a favorabl
Nencki, Marceli
Dictionary entry from: Complete Dictionary of Scientific Biography ...Nencki ’ s best-known investigations concerned hemoglobin. Using original methods he systematically studied for many...products of the pigments and finally obtained, both from hemoglobin and from chlorophyll, the same substance, hemopyrrole...
Fankuchen, Isidor
Dictionary entry from: Complete Dictionary of Scientific Biography ...degree-oscillation X-ray pattern of a single crystal of wet chymotrypsin (set forth in a paper that also dealt with hemoglobin, with Bernal and M. Perutz, 1938). He collaborated in the 1940 monograph on steroids (with Bernal and Crowfoot), in...
Pekelharing, Cornelis Adrianus
Dictionary entry from: Complete Dictionary of Scientific Biography ...role of calcium in blood clotting, arteriosclerosis, urine pigments, enzyme precursors, intestinal iron absorption, and hemoglobin and glycogen in oysters. Pekelharing became interested in nutrition in 1886, when he and Winkler were sent to the Dutch...
affinity
Book article from: The Oxford Pocket Dictionary of Current English ...architectural styles. ∎  relationship, esp. by marriage as opposed to blood ties. ∎  chiefly Biochem. the degree to which a substance tends to combine with another: the affinity of hemoglobin for oxygen.
Elvehjem, Conrad Arnold
Dictionary entry from: Complete Dictionary of Scientific Biography ...investigators, he studied milk-induced anemia and showed that traces of copper are essential for satisfactory iron uptake in hemoglobin formation. Mineral metabolism in animals remained a matter of primary concern and ultimately included work on the roles of...

Related newspaper, magazine, and trade journal articles from HighBeam Research

Hemoglobin C Foils Blood Cell Remodeling: Malaria Protection.
Magazine article from: BIOWORLD Today; 11/3/2009; 700+ words ; ...population. Caused by a mutation in the hemoglobin chain, its effects depend entirely...amino acid substitution in the hemoglobin molecule, the oxygen-carrying molecule in red blood cells. Regular hemoglobin is known as hemoglobin A, whereas...
Hemoglobin Old Dominion/Burton-upon-Trent, (beta 143) (H21) His -> Tyr, Codon 143 CAC -> TAC--a variant with altered oxygen affinity that compromises measurement of glycated hemoglobin in diabetes mellitus: Structure, function, and DNA sequence
Magazine article from: Mayo Clinic Proceedings; 4/1/1998; ; 700+ words ; ...nature and characteristics of a unique hemoglobin variant that causes a spurious increase in glycated hemoglobin (Hb Al). Material and Methods: Blood...from four unrelated persons with this hemoglobin variant were examined by conventional...
Low hemoglobin is red flag for women with chest pain.
Newspaper article from: Hematology Week; 7/12/2004; 700+ words ; ...Women with chest pain who have low hemoglobin levels are more likely to die or suffer...cardiovascular event than women with normal hemoglobin levels, study findings show. According...surprises. "First, women with low hemoglobin levels had a higher rate of death and...
Hemoglobin-based agent reduces need for transfusion during heart surgery.
Newspaper article from: Heart Disease Weekly; 1/12/2003; 700+ words ; ...that an agent made of purified human hemoglobin appears safe and may be effective when...the benefits of the agent, known as hemoglobin raffimer, are proved in subsequent...Anesthesia. The study also showed although hemoglobin raffimer - like other oxygen therapeutics...
WITH HEMOGLOBIN C, MALARIA PARASITE CAN'T HIDE HEMOGLOBIN C FOILS BLOOD CELL REMODELING: MALARIA PROTECTION.
Magazine article from: BIOWORLD Today; 6/28/2005; ; 700+ words ; ...population. Caused by a mutation in the hemoglobin chain, its effects depend entirely...amino acid substitution in the hemoglobin molecule, the oxygen-carrying molecule in red blood cells. Regular hemoglobin is known as hemoglobin A, whereas...
Time of Hemoglobin Elution is Concentration Dependent
Magazine article from: Clinical Chemistry; 6/1/2006; ; 700+ words ; ...identification and quantification of hemoglobin variants because of improved analytical...precision, and throughput. These hemoglobin chromatograms. however, are more difficult...percentages of the variant with libraries of hemoglobin chromatograms. With over 800 variants...
Hemoglobin C and Hemoglobin O-Arab Variants Can Be Diagnosed Using the Bio-Rad Variant II High-Performance Liquid Chromatography System Without Further Confirmatory Tests
Magazine article from: Archives of Pathology & Laboratory Medicine; 4/1/2004; ; 700+ words ; ...test, all non-A, non-S abnormal hemoglobin (Hb) variants must be confirmed by...Design.-We reviewed 48478 consecutive hemoglobin identification test results performed...We identified 3668 cases of abnormal hemoglobin variants, including 660 cases of Hb...
Hemoglobin-Based Agent Reduces Need for Transfusion During Heart Surgery.
News Wire article from: Ascribe Higher Education News Service; 12/12/2002; 700+ words ; ...that an agent made of purified human hemoglobin appears safe and may be effective when...the benefits of the agent, known as hemoglobin raffimer, are proven in subsequent...Anesthesia. The study also showed although hemoglobin raffimer - like other oxygen therapeutics...
Unexpected Hemoglobin A Results after an Erythrocyte Exchange: Importance of Specimen Mixing
Magazine article from: Clinical Chemistry; 6/1/2008; ; 700+ words ; ...procedure increases the percentage of hemoglobin A without dramatically increasing the...erythrocyte exchange is often measured by hemoglobin electrophoresis and densitometry to determine the posttransfusion percentages of hemoglobin A and S. We performed a manual erythrocyte...
Hemoglobin Profiles and Hematologic Features of Thalassemic Newborns: Application to Screening of [alpha]-Thalassemia 1 and Hemoglobin E
Magazine article from: Archives of Pathology & Laboratory Medicine; 11/1/2008; ; 700+ words ; ...disorders is significant, study of the hemoglobin and hematologic features of normal and...is necessary. Objective.-To study hemoglobin and hematologic characteristics of normal...methods for α-thalassemia 1 and hemoglobin E. Design.-Study was made of 402...