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Capsaicin activation of the pain receptor, VR1: Multiple open states from both partial and full binding
Magazine article from: Biophysical Journal; 5/1/2003; ; 700+ words
; ABSTRACT Capsaicin, the pungent ingredient of hot peppers, has...the durations of the interburst gaps vary with capsaicin, the bursts also appeared ligand-dependent, with high capsaicin prolonging bursts and stabilizing openings...
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Topical capsaicin NNTs.
Magazine article from: Bandolier; 7/1/1996; 700+ words
; ...days. When we were asked about topical capsaicin we were relieved to find a well done...allowed the calculation of NNTs [1]. Capsaicin This is an alkaloid from chillies that...interest concerns the use of topical capsaicin as an analgesic for conditions where...
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Topical capsaicin may not help relieve itch induced by serotonin
Magazine article from: Dermatology Times; 6/1/2000; ; 700+ words
; Magdeburg, Germany - Topical capsaicin appears to lack antipruritic potency...serotonin probably does not play a role in capsaicin's mechanism of action. "I expected this result. The mechanism of capsaicin has nothing to do with serotonin...
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Translational vignette: Capsaicin
Magazine article from: Regional Anesthesia and Pain Medicine; 7/1/1999; ; 700+ words
; Capsaicin is a chemical irritant that is the active...chili peppers of the genus Capsicum. Capsaicin has been studied extensively to exploit...information about the mechanism of action of capsaicin at the cellular level has been derived...
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Spicing up health with CAPSAICIN
Magazine article from: Natural Foods Merchandiser; 7/1/2008; ; 700+ words
; ...or capsicum, and one of its active components, capsaicin. Capsaicin's potential to enhance weight loss has made its...The five naturally occurring capsaicinoids include capsaicin, dihydrocapsaicin, nordihydrocapsaicin, homocapsaicin...
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CAPSAICIN RECEPTOR EXPRESSION IN RAT LARYNGEAL INNERVATION
Magazine article from: The Annals of Otology, Rhinology & Laryngology; 5/1/2004; ; 700+ words
; Capsaicin elicits a sensation of burning pain by...VRL-1) are activated, not only by capsaicin, but also by noxious heat and protons...1. These findings suggest that these capsaicin receptors play an important role in the...
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Capsaicin's popularity prompts product intros. (capsaicin-containing topical analgesics)
Magazine article from: Chain Drug Review; 8/11/1997; 700+ words
; ...popularity of topical analgesics with capsaicin, new products with the pepper plant...welcome additions to the category. "Capsaicin may be hot to the touch, but it's...Suppliers that are helping boost the capsaicin segment with new product launches include...
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Peppers for pain: studies have confirmed capsaicin's use as a topical analgesic. Others show it may be useful when consumed, also. (Formulating for Wellness).(Brief Article)
Magazine article from: Prepared Foods; 9/1/2002; 700+ words
; ...the credit at the end of this article. Capsaicin is the primary pungent compound found...genus Capsicum). The chemical name of capsaicin is trans-8 methyl N-vanillyl-nonenamide...clinical studies have confirmed that capsaicin has analgesic properties when applied...
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Cough reflex and oral chemesthesis induced by capsaicin and capsiate in healthy never-smokers.(Research)
Magazine article from: Cough; 10/31/2007; ; 700+ words
; ...Although many tussive agents, such as capsaicin, citric acid, and acetic acid, are...number of tussive agents have been tried, capsaicin has stood the test of time and nowadays...umami, the oral sensation induced by capsaicin is called chemesthesis, a sensation...
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Regulation of galanin and galanin receptor 2 expression by capsaicin in primary cultured dorsal root ganglion neurons
Magazine article from: In Vitro Cellular & Developmental Biology; 9/1/2008; ; 700+ words
; ...plays a pronociceptive role and enhances capsaicin-induced nociception in the periphery...are co-expressed in DRG neurons. Capsaicin evokes acute pain via activation of VR1...receptor GalR2 expression is regulated by capsaicin in DRG neurons. Effects of acute (4...
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