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proline

proline (prō´lēn), organic compound, one of the 20 amino acids commonly found in animal proteins. Only the l-stereoisomer appears in mammalian protein. It is not essential to the human diet, since it can be synthesized in the body from glutamic acid. The amino group through which it can link to other amino acids (see peptide, protein) is part of a circlelike array of atoms—unique to proline. This is significant because when the amino acid is incorporated into protein, its peculiar structure leads to sharp bends, or kinks, in the peptide chain, thus figuring prominently in the determination of the protein's shape. Proline and its derivate hydroxyproline, make up some 21% of the amino-acid residues found in collagen, the fibrous protein of connective tissue. Its chemical synthesis was accomplished in 1900; in 1901 proline was isolated from casein, the milk protein, and its structure was shown to be the same as that of the synthetic compound.

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"proline." The Columbia Encyclopedia, 6th ed.. . Encyclopedia.com. 28 Jun. 2017 <http://www.encyclopedia.com>.

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"proline." The Columbia Encyclopedia, 6th ed.. . Retrieved June 28, 2017 from Encyclopedia.com: http://www.encyclopedia.com/reference/encyclopedias-almanacs-transcripts-and-maps/proline

proline

proline A heterocyclic, non-polar (see NON-POLAR MOLECULE) imino acid, which is present in all proteins studied to date.

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"proline." A Dictionary of Plant Sciences. . Encyclopedia.com. 28 Jun. 2017 <http://www.encyclopedia.com>.

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"proline." A Dictionary of Plant Sciences. . Retrieved June 28, 2017 from Encyclopedia.com: http://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/proline

proline

proline A heterocyclic, non-polar imino acid that is present in all proteins studied to date.

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"proline." A Dictionary of Zoology. . Encyclopedia.com. 28 Jun. 2017 <http://www.encyclopedia.com>.

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proline

proline (proh-leen) n. an amino acid found in many proteins.

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"proline." A Dictionary of Nursing. . Encyclopedia.com. 28 Jun. 2017 <http://www.encyclopedia.com>.

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proline

proline A non‐essential amino acid.

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"proline." A Dictionary of Food and Nutrition. . Encyclopedia.com. 28 Jun. 2017 <http://www.encyclopedia.com>.

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"proline." A Dictionary of Food and Nutrition. . Retrieved June 28, 2017 from Encyclopedia.com: http://www.encyclopedia.com/education/dictionaries-thesauruses-pictures-and-press-releases/proline

proline

proline See amino acid.

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"proline." A Dictionary of Biology. . Encyclopedia.com. 28 Jun. 2017 <http://www.encyclopedia.com>.

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