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isoniazid

A Dictionary of Nursing

isoniazid (isonicotinic acid hydrazide, INH) (I-soh-ny-ă-zid) n. a drug used in the treatment of tuberculosis, usually taken by mouth. Because tuberculosis bacteria soon become resistant to isoniazid, it is given in conjunction with other antibiotics.

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© A Dictionary of Nursing 2008, originally published by Oxford University Press 2008.

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	Mycobacterium tuberculosis drug resistance, Ghana.(Letter to the editor) ; ...8-month course of streptomycin, isoniazid, rifampin, and pyrazinamide (for 2 months), followed by thiacetazone and isoniazid (6 months). The cure rate for 2003...method on LJ media). Sensitivity to isoniazid, rifampin, pyrazinamide, ethambutol... Read more
	Human and animal infections with Mycobacterium microti, Scotland.(DISPATCHES)(Report) ; ...diagnosed in 2001. She was treated with isoniazid, rifampin, ethambutol, and pyrazinamide...and for 4 months more with rifampin and isoniazid. She made good clinical progress, but...were negative. She was re-treated with isoniazid, rifampin, ethambutol, and pyrazinamide... Read more
	Pure red blood cell aplasia and isoniazid use.(LETTERS)(Clinical report) ; To the Editor: Isoniazid is a first-line drug in the treatment...include prevention as well as cure. Isoniazid is usually well tolerated, although...implicated (2), and few reports involving isoniazid have been published. We report a case... Read more
	Antimycobacterial Therapy for Tuberculosis. ; ...patients with fully susceptible organisms is isoniazid, rifampin, pyrazinamide, and ethambutol...daily (or two or three days per week) isoniazid and rifampin therapy for an additional...organism is found to be sensitive to isoniazid and rifampin, the ethambutol or streptomycin... Read more
	Effect of rifampicin & isoniazid on cytochrome P-450 in mycobacteria ; Background & objectives: Rifampicin and isoniazid are the most important first line drugs...We report the effect of rifampicin and isoniazid on the cytochrome P-450 activity in Mycobacterium...Subinhibitory concentrations of rifampicin and isoniazid were added to the organisms after they... Read more
	Action of metronidazole in combination with isoniazid & rifampicin on peristing organisms in experimental murine tuberculosis ; ...tuberculosis and, after 14 days, treated with isoniazid (H) or rifampicin (R) or isoniazid + rifampicin (HR) for 2 months. An untreated...with bactericidal drugs such as rifampicin and isoniazid may be of value in eliminating persisting tubercle... Read more
	Isoniazid ; What is it? Isoniazid (eye-soe-NYE-a-zid), sold as a generic...ever have had an unusual reaction to isoniazid, ethionamide (such as Trecator-SC...any other special diet. Pregnancy - Isoniazid has not been shown to cause birth defects... Read more
	Penetrating the secrets of tuberculosis. ; ...Today's scientific faithful view two drugs, isoniazid and pyrazinamide (PZA), with almost equal...separately, their research meshes well because isoniazid and PZA, while very different, have a...enzyme called catalase, which activates isoniazid. When isoniazid is active, it interferes... Read more
	Multidrug-resistant tuberculosis ; ...Mycobacterium tuberculosis resistant to both isoniazid and rifampicin with or without resistance...With the availability streptomycin, isoniazid and paraaminosalicylic acid (PAS), in...of M. tuberculosis resistant to both isoniazid and rifampicin with or without resistance... Read more
	Seizures, Metabolic Acidosis and Coma Resulting from Acute Isoniazid Intoxication ; SUMMARY Isoniazid is an anti-tuberculosis drug, used commonly...and prophylaxis of tuberculosis. Acute isoniazid intoxication is characterized by a clinical...in a dose equivalent to the amount of isoniazid ingested, is the only effective antidote... Read more

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	isoniazid ...tuberculosis . Also known as isonicotinic acid hydrazide, isoniazid is the most effective antituberculosis drug currently available...individuals who have a positive reaction to a tuberculin skin test, isoniazid is given alone. Side effects are seen only with very high... Read more
	INH INH n. see isoniazid . Read more
	INH INH Med. isonicotinic acid hydrazide (isoniazid; antituberculosis drug) Read more
	antivitamins ...function of vitamin K , thiaminase in raw fish destroys vitamin B1 , the drug methotrexate antagonizes folic acid metabolism (this is part of its mechanism of action in treating cancer), the drug isoniazid antagonizes the action of vitamin B6 . Read more
	pyridine ...C5H5N). Natural compounds with pyridine rings include niacin and pyridoxine ( vitamin B complex ), the tuberculosis drug isoniazid, and several plant products (e.g., nicotine ). Pyridine is used as a raw material for various drugs, vitamins, and fungicides... Read more

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