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Recall of Isoniazid Used for Antimicrobial Susceptibility Testing for Tuberculosis.(Brief Article)
; ...voluntary recall of a lot of isoniazid [INH] (drug lot no. 9335260) used for antimicrobial...Mycobacterium tuberculosis. The recalled INH lot was sold as components of BACTEC [TM...labeled inadvertently as the recalled lot of INH. A second lot of INH (drug lot no. 0077261...
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Severe isoniazid-associated hepatitis - New York, 1991-1993. (preventive therapy for tuberculosis linked to hepatitis)
; ...that developed during the use of isoniazid (INH) preventive therapy (IPT) for latent tuberculous...patients who had hepatitis attributed to INH. This report summarizes findings of the...of severe acute hepatitis attributed to INH. Patients, relatives, and health-care providers...
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Selective serotonin reuptake inhibitors and isoniazid: Evidence of a potential adverse interaction
; ...potential interaction between isoniazid (INH), a weak monoamine oxidase inhibitor, and...with a treatment plan (e.g., 12 months of INH therapy). Patients on both medications constituted...group; patients taking either an SSRI or INH alone constituted comparison groups. Results...
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Isoniazid causing pleural effusion
; ...for which antitubercular drugs (rifampicin, isoniazid [INH], pyrazinamide, and ethambutol) had been started 2 months...effusion persisted. Considering the possibility of an INH-induced effusion, INH was stopped, upon which the patient started showing...
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The Vietnamese Khin Population Harbors Particular N-Acetyltransferase 2 Allele Frequencies
; ...previously untreated patients consists of 2 months of streptomycin, isoniazid (INH), rifampin, and pyrazinamide, followed by 6 months of INH and ethambutol (the 2SHRZ/6HE regimen). INH, a central component of this chemotherapy, is extensively metabolized...
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Molecular Dynamics Simulation Studies of the Wild-Type, I21V, and I16T Mutants of Isoniazid-Resistant Mycobacterium tuberculosis Enoyl Reductase (InhA) in Complex with NADH: Toward the Understanding of NADH-InhA Different Affinities
; ...combination of drugs including isoniazid (INH), rifampicin, pyrazinamide, and ethambutol...of MTB, defined as resistant to at least INH and rifampicin (the two most powerful anti-...controlling drug-sensitive and drug-resistant TB. INH has been the cornerstone in TB chemotherapy...
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Photoreaction Between Benzoylthiophenes and N-BOC-Tryptophan Methyl Ester[double dagger]
; ...2-benzoylthiopheneketyl radical; BTH-BTH, pinacols; CH^sub 3^In, N-centered indolyl radicals; CH^sub 2^InH, C-centered skatolyl radicals; CH^sub 3^InH, 3-methylindole; In, indolyl; InH, indol; In-In, Indol dimmers; SUP, suprofen; TPA, tiaprofenic acid; Trp, tryptophan...
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Urine levels of rifampicin & isoniazid in asymptomatic HIV-positive individuals
; ...absorption of rifampicin (RMP) and isoniazid (INH) in asymptomatic HIV- positive individuals...Intestive. Methods: The absorption of RMP, INH and D-xylose was studied in 15 asymptomatic...administration of single doses of RMP (450 mg), INH (300 mg) and D-xylose (5 g). Urine was collected...
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Low-dose inhaled versus standard dose oral form of anti-tubercular drugs: Concentrations in bronchial epithelial lining fluid, alveolar macrophage and serum
; ...concentrations of rifampicin (RIF), isoniazid (INH) and pyrazinamide (Z) in the epithelial...micro-particles of anti-tubercular drugs (ATD, INH 15 mg, RIF 30 mg and Z 75 mg with lactose...oral ATD (a tablet containing RIF 500 mg, INH 250 mg and Z 1250 mg) as a single dose at...
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Hepatotoxicity of isoniazid: A study on the activity of marker enzymes of liver toxicity in serum and liver tissue of rabbits
; Sir, Isoniazid (INH) is used as a first-line drug in the treatment and chemoprophylaxis...measurement of serum transaminases is often advocated during INH administration, to assess the extent of INH-induced hepatotoxicity.[1] Though a study conducted in rabbits...
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