Conjugated Linoleic Acid Isomers Reduce Blood Cholesterol Levels but Not Aortic Cholesterol Accumulation in Hypercholesterolemic Hamsters

Lipids | January 1, 2006| | Copyright

ABSTRACT: The aim of the present study was to characterize plasma lipids and lipoprotein cholesterol and glucose concentrations in hamsters fed either cis-9,trans-11 CLA (9c,11t CLA); trans-10,cis-12 CLA (10t,12c CLA); or linoleic acid (LA) on the accumulation of aortic cholesterol in hypercholesterolemic hamsters. One hundred male F^sub 1^B strain Syrian Golden Hamsters (Mesocricetus auratus) (BioBreeders Inc., Watertown, MA) approximately 9 wk of age were housed in individual stainless steel hanging cages at room temperature with a 12-h light/dark cycle. Hamsters were given food and water ...

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