Synthesis of extracellular matrix proteins in bovine mammary epithelial cells

From: In Vitro Cellular & Developmental Biology | Date: November 1, 2001| Author: Matitashvili, Elvina; Bauman, Dale E | Copyright information

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Extracellular matrix (ECM) is a highly organized network of proteins, proteoglycans, and glycosaminoglycans, which surrounds cells in many tissues. Numerous studies with rodents have shown unequivocally that normal cell-matrix interactions are indispensable for the survival, growth, and functional differentiation of mammary epithelial cells in vivo and in vitro (Adams and Watt, 1993; Boudreau et al., 1995; Hagios et al., 1998). In studies of Hahm et al. (1990), ECM isolat...

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