(Beta)-carotene alters the morphology of NCI-H69 small cell lung cancer cells

The Journal of Nutrition | January 1, 2002| | Copyright

Nutrition and Cancer-Research Communication

beta-Carotene Alters the Morphology of NCI-H69 Small Cell Lung Cancer Cells1

ABSTRACT The effect of beta-carotene on the morphology of NCI-H69 small cell lung cancer cells that had undergone beta-carotene-induced growth reduction (P < 0.05) was examined. The cells were grown at 1 x 10^sup 8^ cells/L and were cultured with or without 20 (mu)mol/L beta-carotene. The qualitative electron microscopic observations revealed that beta-carotene-treated cells contained more vacuoles than control cells not treated with beta-carotene. The quantitative ...

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