Biological Half-life of Bromide in the Rat Depends Primarily on the Magnitude of Sodium Intake

From: Physiological Research | Date: November 1, 2005| Author: | Copyright information

Summary

The parallel course of the excretion rates of bromide and sodium ions was demonstrated in adult male and female rats administered simultaneously with potassium ^sup 82^Br-bromide and ^sup 24^Na-sodium chloride. The animals were exposed to various intakes of sodium ions accompanied with five different anions: Br-, Cl-, HCO^sub 3^^sup -^, ClO^sub 4^^sup -^, and SCN^sup -^. Regardless of the anion accompanying the sodium ion, the excretion rates of ^sup 82^Br- and ^sup 24^Na+ ions were proportional to the magnitude of sodium intake in the animals. Hence, we have proved our hypothesis ...

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