Proteinase inhibitors induce selective stimulation of human trypsin and chymotrypsin secretion

The Journal of Nutrition | March 1, 1996| | Copyright

Inhibitors of digestive enzymes are widely distributed in food. Soybeans are an increasingly important nutritional source of protein containing protease or trypsin inhibitors. The two main families of soybean trypsin inhibitor are the Kunitz trypsin inhibitor (KTI)(1) (Kunitz 1947a, 1947b) and the Bowman-Birk inhibitor (BBI) (Birk 1985, 1987). Kunitz trypsin inhibitor is a protein of 21 kDa, including two disulfide bridges; BBI has a molecular weight of 8 kDa with a high content of cysteine, forming seven disulfide bridges. Both inhibitors are known to inhibit human trypsin as well as ...

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