New Target Found to Fight Parkinson's

From: USA Today | Date: October 1, 2005| Author: | Copyright information

NEUROLOGY

Neuroscientists have described for the first time how rotenone, an environmental toxin linked specifically to Parkinson's disease, selectively destroys the neurons that produce dopamine, the neurotransmitter critical to body movement and muscle control. Microtubules, intracellular highways that transport dopamine to the brain area that controls body movement, are the crucial target, point out researchers from the University at Buffalo (N.Y).

Damage to microtubules prevents dopamine from reaching the brain's movement center, causing a backup of the neurotransmitter in the transport ...

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