Regenerative Medicine of the Trachea: The First Human Case

The Annals of Otology, Rhinology & Laryngology | June 1, 2005| | Copyright

Objectives: The objective of the present study was to demonstrate regenerative medicine of the trachéal tissue by using an in situ tissue engineering technique for airway reconstruction.

Methods: Based on the previous successful experimental animal studies, the current regenerative technique was applied to repair of the trachea of a 78-year-old woman with thyroid cancer. A Marlex mesh tube covered by collagen sponge was used as a tissue scaffold. The operative intervention included right hemithyroidectomy, resection of the trachea, and tracheoplasty using the scaffold. The right half of ...

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