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Trans-10, cis-12, but not cis-9, trans-11, conjugated linoleic acid attenuates lipogenesis in primary cultures of stromal vascular cells from human adipose tissue
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Trans-10, Cis-12, But Not Cis-9, Trans-11, Conjugated Linoleic Acid Attenuates Lipogenesis in Primary Cultures of Stromal Vascular Cells from Human Adipose Tissue1
ABSTRACT We have previously shown that both a commercially available mixture of conjugated linoleic acid (CLA) isomers and the trans-10, cis-12 isomer of CLA reduced the triglyceride (TG) content and induced apoptosis in differentiating cultures of murine 3T3-11 preadipocytes. However, the influence of CLA isomers on differentiating human (pre)adipocytes is unknown. Therefore, we conducted a series of studies using primary ...
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Oleic acid prevents apoptotic cell death induced by trans10, cis12 isomer of conjugated linoleic acid via p38 MAP kinase dependent pathway
Magazine article from: In Vitro Cellular & Developmental Biology
; ...trans10, cis12 (t10, c12)-conjugated linoleic acid in rat hepatoma dRLh-84 cells. The...cytotoxicity of t10, c12-conjugated linoleic acid. In addition, SubG1 cell population...irrespective of t10, c12-conjugated linoleic acid stimulation. Interestingly, t10, c12-conjugat...
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Dietary linoleic acid intake controls the arterial blood plasma concentration and the rates of growth and linoleic acid uptake and metabolism in hepatoma 7288CTC in Buffalo rats
Magazine article from: The Journal of Nutrition
; ...In this study, we tested the hypothesis that dietary linoleic acid intake controls the arterial blood plasma linoleic acid concentration and the rates of tumor growth and linoleic acid metabolism in vivo. Seven groups of young male Buffalo...
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This fat may aid spread of breast cancer. (diets high in linoleic acid linked to spread of breast cancer in mice) (Brief Article)
Magazine article from: Science News
; ...researchers noted that diets high in linoleic acid -- a nutrient the body needs but must...compared how different proportions of linoleic acid -- accounting for approximately 8 percent...animals eating the diet containing more linoleic acid, the scientists report in the Dec...
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Conjugated linoleic acid inhibits proliferation but stimulates lipid filling of murine 3T3-L1 preadipocytes
Magazine article from: The Journal of Nutrition
; Conjugated Linoleic Acid Inhibits Proliferation but Stimulates...documented the effects of conjugated linoleic acid (CLA) on the proliferation and...96 h postinoculation. Conjugated linoleic acid was not cytotoxic during proliferation...
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Trans-10, cis-12 conjugated linoleic acid increases fatty acid oxidation in 3T3-L1 preadipocytes
Magazine article from: The Journal of Nutrition
; Trans-10, Cis-12 Conjugated Linoleic Acid Increases Fatty Acid Oxidation in 3T3-...mu)mol/L trans-10, cis-12 conjugated linoleic acid (CLA) and cis-9, trans-11 CLA isomers...BSA controls. In contrast, ~50 Amol/L linoleic acid (LA) and cis-9, trans-11 CLA-treated...
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Production of free conjugated linoleic acid by Lactobacillus acidophilus and Lactobacillus casei of human intestinal origin1
Magazine article from: Journal of Dairy Science
; ...was used for analysis of conjugated linoleic acid (CLA) isomers cis-9, trans-11-octadecadienoic...their ability to produce CLA from free linoleic acid in MRS broth supplemented with linoleic acid. Different concentrations of linoleic...
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Trans-10,cis-12 conjugated linoleic acid suppresses the desaturation of linoleic and (alpha)-linolenic acids in HepG2 cells
Magazine article from: The Journal of Nutrition
; Trans-10,cis-12 Conjugated Linoleic Acid Suppresses the Desaturation of Linoleic...were determined. In the presence of linoleic acid as substrate, cells treated with 25...cis-12 CLA had lower ratios of dihomo-y-linoleic acid to linoleic acid and of arachidonic...
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Thermal Polymerisation and Autoxidation of Technical Grade Linoleic Acid
Magazine article from: JAOCS, Journal of the American Oil Chemists' Society
; ...Oligomerisation of technical grade linoleic acid was studied over a broad temperature...Oligomerisation of technical grade linoleic acid was seen to be dependent on temperature...kinetic model was proposed for the linoleic acid oligomerisation giving good model predictions...
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Increasing Homicide Rates and Linoleic Acid Consumption Among Five Western Countries, 1961-2000
Magazine article from: Lipids
; ...intakes of long chain n-3 FA or reducing linoleic acid intake may reduce aggressive and violent...correlate with greater risk of homicide. Linoleic acid available for human consumption was...authority of each country. Apparent linoleic acid intake from seed oil sources ranged...
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Factors Affecting Conjugated Linoleic Acid Content in Milk and Meat
Magazine article from: Critical Reviews in Food Science and Nutrition
; Conjugated linoleic acid (CLA) has been recently studied...atherogenesis, and diabetes. Conjugated linoleic acid (CLA) is a collective term for...positional and geometrical isomers of linoleic acid, which are found in relative abundance...
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