Line Tension and Interaction Energies of Membrane Rafts Calculated from Lipid Splay and Tilt

From: Biophysical Journal | Date: February 1, 2005| Author: Akimov, Sergey A; Chizmadzhev, Yuri A; Cohen, Fredric S; Zimmerberg, Joshua; Kuzmin, Peter I | Copyright information

ABSTRACT

Membrane domains known as rafts are rich in cholesterol and sphingolipids, and are thought to be thicker than the surrounding membrane. If so, monolayers should elastically deform so as to avoid exposure of hydrophobic surfaces to water at the raft boundary. We calculated the energy of splay and tilt deformations necessary to avoid such hydrophobic exposure. The derived value of energy per unit length, the line tension γ, depends on the elastic moduli of the raft and the ...

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