Dynamic ^sup 13^N-Ammonia PET: A New Imaging Method to Diagnose Hypopituitarism

From: The Journal of Nuclear Medicine | Date: January 1, 2005| Author: | Copyright information

We have developed a new imaging method to evaluate the blood perfusion and ammonia metabolism of the pituitary gland, and we preliminarily assessed its role in the diagnosis of hypopituitarism. Methods: Six female healthy volunteers (age range, 20-46 y) and 6 female patients (age range, 23-42 y) were enrolled in this study. Dynamic ^sup 13^N-NH^sub 3^ PET was performed. Time-activity curves for the pituitary gland and internal carotid artery were generated by setting regions of interest on the transverse planes of the pituitary gland. The standardized uptake value of the pituitary gland, the ...

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