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Bone-Seeking Radionuclides for Therapy
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Systemic therapy using bone-seeking radiopharmaceuticals has clear advantages for the treatment of multisite metastatic pain. Evidence supporting the use of β-particle, electron, and α-particle-emitting radiopharmaceuticals is reviewed here. Appropriate patient selection relies on correlating clinical symptoms with focal abnormalities on conventional bone scintigraphy. Time to symptom relief and response duration vary with the physical half-life and dose rate of the radionuclide use...
Related newspaper, magazine, and journal articles from HighBeam Research
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A Pragmatic Perspective on Molecular Targeted Radionuclide Therapy
The Journal of Nuclear Medicine
; ... on targeted radionuclide therapy provides a snapshot of ... involved in radionuclide therapy to provide them with a ... MOLECULAR NATURE OF TARGETED THERAPY Targeted therapy is predominantly molecular ... as interaction with the bone-seeking radionuclide and the hydroxyapatite ... CURRENT ...
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Samarium-153 ethylenediamine tetramethylene phosphonate therapy for bone pain palliation in skeletal metastases
Indian Journal of Cancer
; ... drowsiness. Chemotherapy or hormonal therapy may be used for both soft tissue ... radiation fields.[1] Systemic therapy with radionuclides linked to bone seeking agents, is a treatment option ... low cost and low toxicity.[2] Radionuclides suitable for systemic metabolic ... range of beta ...
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Strontium-89 therapy for painful osseous metastatic prostate and breast cancer.
American Family Physician
; ... radiopharmaceutical has since been well documented. Other radionuclides that demonstrate preferential localization in ... lack of therapeutic effectiveness, none of these radionuclides, except are currently used for therapy, and [sup.32]P is only used in limited circumstances ... radioactive beta-particle ...
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Strontium 89 in the treatment of pain due to diffuse osseous metastases: A university hosptial experience
Journal of the National Medical Association
; ... external beam radiation therapy in the treatment of multiple ... Intravenous injections of bone seeking radioisotopes are effective ... bone pain * palliative therapy * Strontium 89 Skeletal ... radiotherapy, bisphosphonates and bone seeking radioisotopes4. Analgesic therapy using ...
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Clinical Practice of Molecular Radiotherapy
The Journal of Nuclear Medicine
; ... the first forms of targeted therapy in cancer medicine, has been ... used in targeted radionuclide therapy. Furthermore, the fairly recent ... Molecular Targeted Radionuclide Therapy," written by the 2 editors ... actively involved in radionuclide therapy to provide them with a summary ... various forms ...
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