Absence of cytomegalovirus infection in children with acquired immunodeficiency syndrome and distal sensory polyneuropathy From: Journal of Pediatric Neurology | Date: October 1, 2004| Author: de Q C Araà º jo, Alexandra P; Couglan, Suzie; Hall, William W | Copyright Journal of Pediatric Neurology Oct-Dec 2004. Provided by ProQuest LLC.Copyright information

Abstract

To investigate the role of cytomegalovirus (CMV) infection in the pathogenesis of peripheral neuropathy in children with acquired immunodeficiency syndrome (AIDS) a cross-sectional descriptive study was conducted on a sample of nine children. Plasma samples were tested for CMV DNA by two polymerase chain reaction assays (sensitivity limits of 400 and 10 copies/mls) respectively. While all nine were CMV seropositive all were negative for viremia in both assays. CMV would appear...